Month: November 2022

Chiral-at-Iron Catalyst: Expanding the Chemical Space for Asymmetric Earth-Abundant Metal Catalysis was written by Hong, Yubiao; Jarrige, Lucie; Harms, Klaus; Meggers, Eric. And the article was included in Journal of the American Chemical Society on March 20,2019.Reference of 1045894-43-6 The following contents are mentioned in the article:

A new class of chiral iron catalysts is introduced that contains exclusively achiral ligands with the overall chirality being the result of a stereogenic iron center. Specifically, iron(II) is cis-coordinated to two N-(2-pyridyl)-substituted N-heterocyclic carbene (PyNHC) ligands in a bidentate fashion in addition to two monodentate acetonitriles, and the dicationic complex is complemented by two hexafluorophosphate ions. Depending on the helical twist of the PyNHC ligands, the metal center adopts either a Λ or Δ absolute configuration. Importantly, the two PyNHC ligands are constitutionally and configurationally inert, while the two acetonitriles are labile and allow asym. transition metal catalysis. This is demonstrated with an enantioselective Cannizzaro reaction (96% yield, 88% ee) and an asym. Nazarov cyclization (89% yield, >20:1 dr, 83% ee). This study involved multiple reactions and reactants, such as (R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6Reference of 1045894-43-6).

(R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6) belongs to oxazolidine derivatives.Oxazolidines are readily available also from propargyl amines. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Reference of 1045894-43-6

1045894-43-6;(R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol;The future of 1045894-43-6;New trend of C12H15NO2;function of 1045894-43-6

2-(4′,4′-Dimethyl-3′,4′-dihydrooxazol-2′-yl)phenol: some first-row transition metal complexes of this naturally occurring binding group was written by Mugesh, Govindasamy; Singh, Harkesh B.; Butcher, Ray J.. And the article was included in European Journal of Inorganic Chemistry on March 31,2001.Formula: C11H13NO2 The following contents are mentioned in the article:

The synthesis and characterization of monomeric MnIII, CoII, NiII, CuII, and ZnII phenolates derived from a biol. relevant ligand, 2-(4′,4′-dimethyl-3′,4′-dihydrooxazol-2′-yl)phenol (1), are described. The addition of Mn(OAc)2·4H2O to an EtOH solution of 1 affords an unexpected 1:3 [Mn(OR){O(Ox)}2] (2) [R = o-C6H4CONHC(Me2)CH2OH, Ox = 2-(4,4-dimethyl-2-oxazolinyl)phenyl] in which one of the five-membered oxazoline rings is partially hydrolyzed. [M{O(Ox)}2] [M = Co (3), Ni (4), Cu (6), or Zn (7)] were prepared in good yield by the reactions of 1 with the corresponding metal acetates. Novel formation of the six-coordinate NiII complex (Ni{O(Ox)}2(OAc)2, 5) with neutral HOAc was observed during the crystallization process. The complexes were characterized by elemental anal., magnetic susceptibility, as well as EPR, 1H NMR, electronic, and mass spectral techniques. 2, 3, 5, 6, And 7 were characterized by single crystal x-ray diffraction studies. 2 Is six-coordinate whereas 3, 6, and 7 are four-coordinate with two bidentate oxazoline ligands. The geometry around the metal center is distorted tetrahedral for all of the four-coordinate complexes. Complex 5 is octahedral with four coordination sites occupied by the two bidentate oxazoline ligands and the other two are occupied by two neutral HOAc mols. The hydroxy groups of the coordinated HOAc are H-bonded to the phenolate O atoms of the oxazoline ligands. The variable-temperature 1H NMR spectroscopic studies of 7 indicate that the interconversion between the (M) and (P) helix is slow at low temperatures This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Formula: C11H13NO2).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.Formula: C11H13NO2

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

New phosphite-oxazoline ligands for efficient Pd-catalyzed substitution reactions was written by Pamies, Oscar; Dieguez, Montserrat; Claver, Carmen. And the article was included in Journal of the American Chemical Society on March 23,2005.Recommanded Product: 150699-08-4 The following contents are mentioned in the article:

Nonracemic oxazolinylphenoxy dibenzodioxaphosphepines I (R = Me3C, Ph, Me2CH, Et, H; R1 = H, Ph; R2 = H, Me3C; R3 = H, MeO, Me3C) are prepared from nonracemic oxazolinylphenols and phosphochloridites generated in situ from substituted biphenyldiols; I act as catalysts for enantioselective palladium-catalyzed allylic substitution reactions of cyclic and acyclic allylic acetates with di-Me malonate and benzylamine to give allylic malonates and allylic amines in up to 99% yields and in 42-99% ee. Reaction of 2,2′-biphenols with phosphorus trichloride followed by the addition of nonracemic 4-substituted-2-(2-hydroxyphenyl)oxazolines yields I. In the presence of ligands I (R = H, Ph; R1 = Ph, H; R2 = R3 = Me3C), bis(allylpalladium chloride) acts as a catalyst for enantioselective allylic substitution reactions of 1,3-diphenyl-2-propenyl acetate with either di-Me malonate or benzylamine to yield PhCH:CHCHPhCH(CO2Me)2 or PhCH:CHCHPhNHCH2Ph in 100% conversion and in 98-99% ee. Other allylic acetates such as 3-penten-2-ol acetate, 2-cyclohexenyl acetate, and 1-phenyl-2-propenol acetate undergo palladium-catalyzed regioselective and enantioselective allylic substitution reactions with di-Me malonate to yield products in 74-99% ee; with 1-phenyl-2-propen-1-ol acetate, the product is obtained as a 68:32 mixture of regioisomers with the major regioisomer formed in 86% ee, while 1-(1-naphthyl)-2-propen-1-ol acetate gives a single regioisomer in 92% ee, with both substitution products formed in 100% yield. Ligands I afford excellent reaction rates and enantioselectivities while possessing broad scopes for different substrate types. This study involved multiple reactions and reactants, such as (R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4Recommanded Product: 150699-08-4).

(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4) belongs to oxazolidine derivatives. Oxazolidines that are the precursor to bisoxazolidines are in effect mono-oxazolidines. They are also used as moisture scavengers in polyurethane and other systems. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Recommanded Product: 150699-08-4

150699-08-4;(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol;The future of 150699-08-4;New trend of C15H13NO2;function of 150699-08-4

New phosphite-oxazoline ligands for efficient Pd-catalyzed substitution reactions was written by Pamies, Oscar; Dieguez, Montserrat; Claver, Carmen. And the article was included in Journal of the American Chemical Society on March 23,2005.COA of Formula: C13H17NO2 The following contents are mentioned in the article:

Nonracemic oxazolinylphenoxy dibenzodioxaphosphepines I (R = Me3C, Ph, Me2CH, Et, H; R1 = H, Ph; R2 = H, Me3C; R3 = H, MeO, Me3C) are prepared from nonracemic oxazolinylphenols and phosphochloridites generated in situ from substituted biphenyldiols; I act as catalysts for enantioselective palladium-catalyzed allylic substitution reactions of cyclic and acyclic allylic acetates with di-Me malonate and benzylamine to give allylic malonates and allylic amines in up to 99% yields and in 42-99% ee. Reaction of 2,2′-biphenols with phosphorus trichloride followed by the addition of nonracemic 4-substituted-2-(2-hydroxyphenyl)oxazolines yields I. In the presence of ligands I (R = H, Ph; R1 = Ph, H; R2 = R3 = Me3C), bis(allylpalladium chloride) acts as a catalyst for enantioselective allylic substitution reactions of 1,3-diphenyl-2-propenyl acetate with either di-Me malonate or benzylamine to yield PhCH:CHCHPhCH(CO2Me)2 or PhCH:CHCHPhNHCH2Ph in 100% conversion and in 98-99% ee. Other allylic acetates such as 3-penten-2-ol acetate, 2-cyclohexenyl acetate, and 1-phenyl-2-propenol acetate undergo palladium-catalyzed regioselective and enantioselective allylic substitution reactions with di-Me malonate to yield products in 74-99% ee; with 1-phenyl-2-propen-1-ol acetate, the product is obtained as a 68:32 mixture of regioisomers with the major regioisomer formed in 86% ee, while 1-(1-naphthyl)-2-propen-1-ol acetate gives a single regioisomer in 92% ee, with both substitution products formed in 100% yield. Ligands I afford excellent reaction rates and enantioselectivities while possessing broad scopes for different substrate types. This study involved multiple reactions and reactants, such as (S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8COA of Formula: C13H17NO2).

(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.COA of Formula: C13H17NO2

135948-04-8;(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol;The future of 135948-04-8;New trend of C13H17NO2;function of 135948-04-8

Enantioselective Allylation of Aldehydes with (Dialkoxyallyl)chromium(III) Complexes was written by Sugimoto, Kazuyuki; Aoyagi, Sakae; Kibayashi, Chihiro. And the article was included in Journal of Organic Chemistry on April 18,1997.HPLC of Formula: 163165-92-2 The following contents are mentioned in the article:

A (dialkoxyallyl)chromium(III) complex, chirally modified by an N-benzoyl-L-prolinol derivative, led to high induction in the asym. preparation of homoallylic alcs. by allyl coupling with aldehydes. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2HPLC of Formula: 163165-92-2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.HPLC of Formula: 163165-92-2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

A facile one stage synthesis of oxazolines under microwave irradiation was written by Clarke, David S.; Wood, Robin. And the article was included in Synthetic Communications on April 30,1996.Recommanded Product: 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol The following contents are mentioned in the article:

A rapid, high yielding procedure for the synthesis of 2-substituted oxazolines I (R = Ph, 4-pyridyl, CH2CH2CH2Ph, etc.), has been achieved under microwave irradiation from alkyl and aryl nitriles RCN and H2NCMe2CH2OH using a mild Lewis acid catalyst. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Recommanded Product: 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines that are the precursor to bisoxazolidines are in effect mono-oxazolidines. They are also used as moisture scavengers in polyurethane and other systems. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Recommanded Product: 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

Synthesis and characterization of dialkyl[2-(2-phenolato)oxazolines] of gallium(III) and indium(III): crystal structure of [{InMe2(OC6H4-OxMe2)}2] was written by Ghoshal, Shamik; Wadawale, Amey; Jain, Vimal K.; Nethaji, Munirathinam. And the article was included in Journal of Chemical Research on April 30,2007.Category: oxazolidine The following contents are mentioned in the article:

Reactions of trialkylgallium and -indium etherates with 2-(2-hydroxyphenyl)oxazolines afforded colorless dialkyl[2-(2-phenolato)oxazoline]gallium and -indium complexes I and II (R = Me or Et; Ox = oxazoline, R’ = Me or Et; R” = Me or H). These complexes were characterized by elemental anal., IR, mass and NMR (1H and 13C) spectral data. [{InMe2(OC6H4-OxMe2)}2] has a dimeric structure as established by x-ray diffraction. The In atom acquires an irregular trigonal bipyramidal geometry defined by C2O2N ligating atoms. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Category: oxazolidine).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Category: oxazolidine

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

Synthesis of (hydroxyphenyl)oxazine, (aminophenyl)oxazine and (hydroxyphenyl)diazine derivatives using ytterbium triflate as catalyst was written by Fei, Xue-ning; Berg, David J.. And the article was included in Huaxue Yanjiu Yu Yingyong on May 31,2007.HPLC of Formula: 163165-91-1 The following contents are mentioned in the article:

Oxazine-phenol derivatives are important compounds In this paper, phenolic oxazine derivatives and analogs were synthesized by a reaction of cyanophenols with amino alc. or diamine under the catalysis of Yb(OSO2CF3)3. Factors influencing the outcome of the above-mentioned reactions were studied, such as the position of substituent groups, the type of cyclization reaction and the kinds of solvent selected. The structures of these compounds were confirmed by 1H NMR, 13C NMR, Ms and MP. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1HPLC of Formula: 163165-91-1).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines that are the precursor to bisoxazolidines are in effect mono-oxazolidines. They are also used as moisture scavengers in polyurethane and other systems. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.HPLC of Formula: 163165-91-1

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

Synthesis, characterization and thermal decomposition study of cerium(IV) 2-(2′-hydroxyphenyl)-2-oxazoline derivatives was written by Guillon, Herve; Daniele, Stephane; Hubert-Pfalzgraf, Liliane G.; Letoffe, J. M.. And the article was included in Polyhedron on May 6,2004.Formula: C11H13NO2 The following contents are mentioned in the article:

Ce(IV) oxazoline derivatives Ce(Me2oxaz)4 (1) [Me2oxazH = 2-(2′-hydroxyphenyl-4-dimethyl)oxazoline] and Ce(PriHoxaz)4 (2) [PriHoxazH = 2-(2′-hydroxyphenyl-4-isopropyl)oxazoline] were prepared in high yields by ligand exchange reactions between Ce2(OPri)8(PriOH)2 and the corresponding 2-(2′-hydroxyphenyl)-2-oxazolines. Characterization was achieved by elemental anal., FTIR, 1H NMR and mass spectroscopy. 2 Was also characterized by polarimetric measurement. Their thermal decomposition pathways under N were studied by TGA and coupled TGA-CG/MS experiments This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Formula: C11H13NO2).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. Oxazolidines are commonly used as metal ligands in asymmetric catalysis, synthetic intermediates in organic synthesis, and also used as the protecting groups.Formula: C11H13NO2

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

Lanthanide complexes of an oxazoline-phenoxide hybrid chelate was written by Berg, David J.; Zhou, Chuanjian; Barclay, Tosha; Fei, Xuening; Feng, Shengyu; Ogilvie, Kevin A.; Gossage, Robert A.; Twamley, Brendan; Wood, Mark. And the article was included in Canadian Journal of Chemistry on May 31,2005.HPLC of Formula: 163165-91-1 The following contents are mentioned in the article:

The synthesis of 2-(2′-hydroxy-3′-allylphenyl)-4,4-dimethyl-2-oxazoline, H-Allox (3), and lanthanide tris chelate complexes, mer-Ln(Allox)3 (Ln = La (4), Ce (5), Sm (6), Er (7), and Y (8)), derived from it are reported. A six-coordinate mer geometry without alkene coordination was confirmed in the solid state by x-ray crystallog. for 5 and 7. Variable-temperature NMR experiments suggested that this is the most stable isomer in solution as well, although the inequivalent ligand environments undergo rapid averaging at room temperature for all five complexes. A mechanistic study indicated that this fluxional process is an intramol. six-coordinate rearrangement, but it was not possible to distinguish between a Bailar (trigonal) or Ray-Dutt (rhombic) twist. Kinetic parameters for the fluxional process were determined by line shape anal. for 8 yielding ΔH‡ = 24 ± 2 kJ mol-1 and ΔS‡ = -99 ± 10 J mol-1 K-1. The structural and dynamic features of 4-8 were compared with the related In, Ga, and Al tris(2-oxazolylphenoxides). This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1HPLC of Formula: 163165-91-1).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.HPLC of Formula: 163165-91-1

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1