A new application about (S)-4-Isobutyloxazolidine-2,5-dione

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.3190-70-3. In my other articles, you can also check out more blogs about 3190-70-3

3190-70-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.3190-70-3, Name is (S)-4-Isobutyloxazolidine-2,5-dione, molecular formula is C7H11NO3. In a Article, authors is Smeets£¬once mentioned of 3190-70-3

A scalable synthesis of L-leucine-N-carboxyanhydride

Due to its relevance in the synthesis of well-defined oligopeptides, the L-leucine-N-carboxyanhydride (leucine-NCA) synthesis was selected for fine chemical scale-up with a scope on application on larger scales. The heterogeneous gas-solid-liquid nature of the leucine-NCA synthesis implied a mass transfer limited reaction rate towards phosgenation and was investigated on bench scale. Upon scale increase, the liquid-gas mass transport of HCl is drastically reduced, retarding the reaction and consequently rendering the process unsuitable for scale-up. Addition of an HCl scavenger such as (+)-limonene prevented side reactions thus allowing a cost reduction, a considerably faster reaction, and minimization of the amount of phosgene source used. The modified leucine-NCA synthesis has successfully been made scalable, maintaining high product purity on a 1.0 dm3 scale.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.3190-70-3. In my other articles, you can also check out more blogs about 3190-70-3

Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H1525NO – PubChem