Brief introduction of Oxazolidin-2-one

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497-25-6, Name is Oxazolidin-2-one, belongs to oxazolidine compound, is a common compound. Computed Properties of C3H5NO2In an article, once mentioned the new application about 497-25-6.

Intramolecular inverse electron-demand [4+2] cycloadditions of ynamidyl-tethered pyrimidines: Comparative studies in trifluorotoluene and sulfolane

Three representative 6,7-dihydro-5H-cyclopenta[b]pyridin-4-amines were synthesized using an intramolecular inverse electron demand hetero?Diels?Alder/retro?Diels?Alder sequence between pyrimidines (acting as azadienes) and ynamides (acting as dienophiles). Two solvents of this reaction, sulfolane and trifluorotoluene, were compared at 210 C and the former consistently led to higher yields. In addition, these studies confirmed the importance of the steric bulk of the C5-position of the pyrimidinyl cycloaddition precursor.

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Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H499NO – PubChem