Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. Formula: C3H5NO2. Introducing a new discovery about 497-25-6, Name is Oxazolidin-2-one
Potassium alkenyltrifluoroborate salts undergo coupling with amides to give enamides using a catalytic amount of Cu(OAc)2 under mild oxidative conditions. The air and water stable alkenyltrifluoroborate salts offer a practical alternative to the use of alkenyl halides and alkenylboronic acids as cross-coupling partners. A range of amides participate in the cross-coupling, including heterocyclic amides, imides, carbamates, benzamides, and acetamides. Optimization studies established two sets of conditions, best suited to either high PKa or low PKa amide substrates. Lower PK amide substrates worked best using a dichloromethane solvent system in the presence of 4 A molecular sieves, 10 mol % Cu(OAc)2, and 20 mol % N-methylimidazole. Higher PKa amide substrates worked best using a ligandless protocol using a 1:1 dichloromethane/DMSO solvent system in the presence of 4 A molecular sieves and 10 mol % Cu(OAc)2. The cross-coupling reactions occur stereospecifically with retention of alkene configuration from the alkenyltrifluoroborate salt. The mild reaction conditions employed are tolerant of various functionalities, including nitro, acetals, alkyl and aryl halides, and alpha,beta-unsaturated carbonyls. Finally, the importance of copper sources and the presence of minor impurities were investigated.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Formula: C3H5NO2, you can also check out more blogs about497-25-6
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H354NO – PubChem