Reference of 497-25-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2. In a Article，once mentioned of 497-25-6
LiOtBu Promoted 5-Exo?dig Cyclization of Propargyl Alcohols and Isocyanates for the Synthesis of Multisubstituted 3H-Oxazol-2-ones and Oxazolidin-2-ones
This study presents an efficient procedure for synthesis of 3,4,5-trisubstituted 3H-oxazol-2-ones and 3,4-disubstituted (Z)-oxazolidin-2-ones from substituted propargyl alcohols and aryl/alkyl isocyanates in the presence of LiOtBu, a base, and DMF, a solvent. This one-step, low-cost and gram scale synthesis exhibits superior atom economy, good to excellent yields, enhanced substrate scope and, high functional group tolerance and uses column chromatography-free purifications. Further, a product containing bromo substituent was successfully examined for Suzuki coupling with a view to amplifying the complexity of the molecule. Finally, the three component (aniline, Di-tert-butyldicarbonate and propargyl alcohol) reaction was demonstrated to get the oxazolon-2-ones (3H-oxazol-2-one and oxazolidin-2-one).
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Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H960NO – PubChem