Recommanded Product: 102029-44-7, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 102029-44-7, Name is (R)-4-Benzyl-2-oxazolidinone, molecular formula is C10H11NO2. In a Patent，once mentioned of 102029-44-7
The invention discloses a N – Boc – trans – 4 – methyl – L – proline methyl ester preparation method, compound D – glutamic acid in the diazotization reaction, esterification reaction, hydrolysis to obtain compound 16; compound 16 with TBSCl reaction to obtain compound 17; compound 17 hydrolysis, then with the (R)- 4 – benzyl – 2 – oxazolidinone reaction to obtain compound 18; compound 18 undergo the substitution reaction to obtain compound 19; compound 19 reduction to obtain compound 20, then with the DPPA, DBU reaction, to obtain the compound 21; compound 21 deprotection to obtain compound 22; compound 22 dehydroxylated, and then dissolved in methanol in the reaction under the condition of iodine potassium hydroxide to obtain compound 23; compound 23 deprotected after reaction with P-toluene sulfonyl chloride, to obtain compound 24; compound 24 in the catalytic reaction under the condition of the ring, adding alkaline substance and Boc anhydride reaction to obtain compound 4. Preparation method of the invention overcomes the existing technology in the preparation N – Boc – 4 – methyl proline methyl ester exists when the defect of the stereo selectivity is not good, the use of a readily available and inexpensive starting materials, to improve the yield of the process. (by machine translation)
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Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1632NO – PubChem