Application of 1676-86-4, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1676-86-4, Name is (S)-Benzyl (4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate, molecular formula is C15H18N2O5. In a Article,once mentioned of 1676-86-4
Polymerization of alpha-amino acid N-carboxyanhydrides catalyzed by rare earth tris(borohydride) complexes: Mechanism and hydroxy-endcapped polypeptides
In this work, rare earth tris(borohydride) complexes, Ln(BH 4)3(THF)3 (Ln = Sc, Y, La, and Dy), have been used to catalyze the ring-opening polymerization of gamma-benzyl-L-glutamate N-carboxyanhydride (BLG NCA). All the catalysts show high activities and the resulting poly(gamma-benzyl-L-glutamate)s (PBLGs) are recovered with high yields (?90%). The molecular weights (MWs) of PBLG can be controlled by the molar ratios of monomer to catalyst, and the MW distributions (MWDs) are relatively narrow (as low as 1.16) depending on the rare earth metals and reaction temperatures. Block copolypeptides can be easily synthesized by the sequential addition of two monomers. The obtained P(gamma-benzyl-L-glutamate- b-mu-carbobenzoxy-L-lysine) [P(BLG-b-BLL)] and P(gamma-benzyl-L-glutamate-b- alanine) [P(BLG-b-ALA)] have been well characterized by NMR, gel permeation chromatography, and differential scanning calorimetry measurements. A random copolymer P(BLG-co-BLL) with a narrow MWD of 1.07 has also been synthesized. The polymerization mechanisms have been investigated in detail. The results show that both nucleophilic attack at the 5-CO of NCA and deprotonation of 3-NH of NCA in the initiation process take place simultaneously, resulting in two active centers, that is, an yttrium ALA carbamate derivative [H2BOCH 2(CH)NHC(O)OLni£] and a N-yttriumlated ALA NCA. Propagation then proceeds on these centers via both normal monomer insertion and polycondensation. After termination, two kinds of telechelic polypeptide chains, that is, alpha-hydroxyl-omega-aminotelechelic chains and alpha-carboxylic-omega-aminotelechelic ones, are formed as characterized by MALDI-TOF MS, 1H NMR, 13C NMR, 1H-1H COSY, and 1H-13C HMQC measurements. By decreasing the reaction temperature, the normal monomer insertion pathway can be exclusively selected, forming an unprecedented alpha-hydroxyl-omega-aminotelechelic polypeptide.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 1676-86-4. In my other articles, you can also check out more blogs about 1676-86-4
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H2732NO – PubChem