Category: 16251-45-9

16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, belongs to oxazolidine compound, is a common compound. category: oxazolidineIn an article, once mentioned the new application about 16251-45-9.

Secondary 1,3,2-diazaphospholenes have a polarized P?H bond and are emerging as molecular hydrides. Herein, a class of chiral, conformationally restricted methoxy-1,3,2-diazaphospholene catalysts is reported. We demonstrate their catalytic potential in asymmetric 1,4-reductions of alpha,beta-unsaturated carbonyl derivatives, including enones, acyl pyrroles, and amides, which proceeded in enantioselectivities of up to 95.5:4.5 e.r.

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Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2182NO – PubChem

Application of 16251-45-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, molecular formula is C10H11NO2. In a Patent，once mentioned of 16251-45-9

The invention is a novel series of compounds which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 16251-45-9

Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2125NO – PubChem

Synthetic Route of 16251-45-9, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, molecular formula is C10H11NO2. In a article，once mentioned of 16251-45-9

The present invention provides a compound of the formula STR1 which inhibit squalene synthetase and cholesterol biosynthesis and are useful in the treatment of e.g., hyperlipidaemia, atherosclerosis, or fungal infections, processes for the preparation of the compounds of the invention, intermediates useful in these processes, and pharmaceutical compositions containing the compounds.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 16251-45-9

Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2110NO – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, molecular formula is C10H11NO2

Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the antagonists of PGD2 receptors described herein, as well as methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 16251-45-9, in my other articles.

Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2117NO – PubChem

Application of 16251-45-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 16251-45-9, (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, introducing its new discovery.

Chemical Equation Presentation The stereoselective synthesis of the monocyclic peloruside A analogue 4 has been achieved, following a new efficient approach for the introduction of the side chain, involving a late-stage addition of vinyl lithium species 7a to aldehyde 8. Further key steps are a highly diastereoselective allyltitanation reaction and a RCM-based macrocyclization.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 16251-45-9. In my other articles, you can also check out more blogs about 16251-45-9

Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2195NO – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Formula: C10H11NO2. Introducing a new discovery about 16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one

Fluorinated analogues of bioactive amino sugars are of high interest in medicinal chemistry. We developed a straightforward synthetic route towards this class of carbohydrates by applying a titanium-mediated aldol addition. Thus, two-carbon chain elongations of serine- and threonine-derived aldehydes with a chiral fluoroacetyl-oxazolidinone could be achieved in good yields and excellent diastereoselectivities to generate a fluorohydrin-containing carbon skeleton. A short deprotection sequence subsequently furnished the pyranoid forms of various 4-amino-2-fluoropentoses and -hexoses, respectively. The versatility of this strategy was demonstrated by the stereoselective synthesis of naturally abundant 4-amino-4-deoxyarabinose and 4-amino-4,6-dideoxygalactose (tomosamine). 4-Amino-2-fluoropentoses and -hexoses were prepared through two-carbon chain elongations by Ti-mediated aldol additions of serine- and threonine-derived amino aldehydes to fluoroacetyl-ephedrine-oxazolidinone. Excellent stereoselectivities were attained for matched-case fluorohydrins, which were deprotected in a short sequence. Copyright

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Formula: C10H11NO2, you can also check out more blogs about16251-45-9

Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2137NO – PubChem

Synthetic Route of 16251-45-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, molecular formula is C10H11NO2. In a Patent，once mentioned of 16251-45-9

Methods are disclosed to treat or prevent at least one disease or condition in a subject in need thereof comprising administering a compound of Formula (I): (I) or a pharmaceutically acceptable salt, or ester thereof, wherein R1 and R2 are independently chosen from a hydrogen atom or linear, branched, and/or cyclic C1 -C6 alkyl groups, with the proviso that R1 and R2 are not both hydrogen or a pharmaceutically acceptable salt or ester thereof. Such diseases or conditions may relate to coronary heart disease (CHD), for example atherosclerosis; metabolic syndrome/insulin resistance; and/or a dyslipidemic condition such as hypertriglyceridemia (HTG), elevated LDL- cholesterol, elevated total-cholesterol, elevated Apo B and low HDL-cholesterol. The present disclosure further provides for a method of reducing atherosclerosis development. Pharmaceutical compositions comprising a compound of Formula (I) are also disclosed.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 16251-45-9

Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2116NO – PubChem

Related Products of 16251-45-9, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one,introducing its new discovery.

The potential of di-(-)-isobornyl diazenedicarboxylate (2) to act as a chiral azo-enophile in asymmetric ene reactions was investigated. Azo-enophile (2) was treated with trans-hex-3-ene and cyclohexene in the presence of tin(IV) chloride affording the ene adducts (4) and (5) respectively; however, no diastereoselectivity was observed. The synthesis of the novel chiral diazanedicarboxylates (12), (17) and (19) and the unsuccessful attempts to transform them into the chiral azo-enophiles (11), (16) and (19) bearing chiral oxazolidinone, diacetone-D-glucose and pantolactone chiral auxiliaries are also described.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 16251-45-9, and how the biochemistry of the body works.Related Products of 16251-45-9

Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2146NO – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. category: oxazolidine. Introducing a new discovery about 16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one

The present invention relates to substituted pyrazolopyridinamine compounds of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative, angiogenesis disorders, inflammatory diseases or diseases associated with inflammatory pain, as a sole agent or in combination with other active ingredients.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: oxazolidine, you can also check out more blogs about16251-45-9

Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2120NO – PubChem

16251-45-9, Name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, belongs to oxazolidine compound, is a common compound. Quality Control of (4S,5R)-4-Methyl-5-phenyloxazolidin-2-oneIn an article, once mentioned the new application about 16251-45-9.

The chiral separation of pharmaceuticals is one of the major research topics in the pharmaceutical industry. Chromatographic techniques are most frequently used in this context. Separations in capillary electrochromatography (CEC) are an alternative and achieved by chromatographic retention and electrophoretic mobility principles. As a result, CEC is characterized by a high selectivity and efficiency. The limited number of stationary phases specifically developed for CEC, the low number of commercially available CEC columns, the frits to maintain the stationary phase, which forms fragile spots in the columns, and the limited column robustness and reproducibility, make CEC not very attractive for industrial application. However, CEC is still applied and studied in the academic field. This review discusses the enantioseparation of drugs in CEC published during the last four years, with a critical view on the reproducibility and the practical utility of these applications.

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Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2155NO – PubChem