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Epoxy (EP) modified with nonpolar rubbers have the potential to achieve a concurrent improvement in mechanical and dielectric properties, when the EP-rubber interface is properly manipulated. Here we investigate rubber toughened EP based on a non-polar hydroxyl terminated polybutadiene (HTPB), and a coupling agent, dimer fatty acid diisocyanate (DDI), in which the rubber is covalently bonded to the epoxy. The mechanical and dielectric properties can be improved with the addition of HTPB and are maximized at 15 phr of elastomer inclusion. The enhanced mechanical toughness is attributed to the extensive shear yielding induced by a large amount of uniformly dispersed rubber particles; the same morphology can also combine the good insulating properties of HTPB and dielectrically favorable interfaces. These facts along with the reduced dielectric constant and loss for the modified EP suggest that the HTPB-DDI-EP can be used as a promising insulating packaging material for microelectronic applications.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H704NO – PubChem

 

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Application of 497-25-6, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 497-25-6, molcular formula is C3H5NO2, introducing its new discovery.

A new Michael addition/intramolecular alkylation sequence of (Z)-3-(2-bromo-3-arylacryloyl)oxazolidin-2-ones and malonates was developed. By a simple switch of the reaction conditions including the base promoter, solvent, and reaction temperature, both of the cis- and trans-isomers of a series of oxazolidinone-containing 2,3-disubstituted cyclopropane-1,1-diesters could be obtained in good-to-excellent yields and with an excellent diastereoselectivity. The utility of the cyclopropane products was demonstrated in the diastereoselective syntheses of (±)-urinaligran and a stereoisomer of (±)-virgatusin involving the AlCl3-promoted [3+2] annulation with veraldehyde or piperonal as the key step.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H979NO – PubChem

 

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A series of epoxy resin-modified polyisocyanurate (EP-PIR) foams with oxazolidone (OX) rings and isocyanurate (IS) rings have been successfully prepared by the reaction of polymethylene polyphenyl isocyanate (PAPI) and diglycidyl ether of bisphenol-A (DGEBA). Fourier transform infrared spectroscopy and differential scanning calorimetry are performed to investigate the influence of curing temperature on the chemical structure of EP-PIR foams. The results indicate that low temperature is beneficial to the formation of the IS ring, and high temperature is in favor of the OX ring. The influence of the mole ratio of [PAPI]/[DGEBA] on the mechanical properties and thermal stability has also been studied. With the increase of [PAPI]/[DGEBA], the specific compressive strength shows a maximum of 0.0135 ± 0.0003 MPa m3/kg. The optimized mole ratio of [PAPI]/[DGEBA] is around 2.5 to reach the better mechanical and thermal properties, and the glass-transition temperature is as high as 323.5C.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H422NO – PubChem

 

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A photoredox catalytic approach to synthetically valuable N-acyl-N?-aryl-N,N?-aminals is described. This method uses the addition of a radical precursor to enamides, with subsequent interception of the cationic iminium intermediate with an arylamine. The reaction has been shown to be compatible with electron-rich and electron-deficient arylamines, and moderate to good levels of diastereoselectivity can be attained using a chiral enamide. Furthermore, the N-acyl-N?-aryl-N,N?-aminal reaction products can be readily cyclized, providing a novel synthetic route to valuable gamma-lactams.

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Oxazolidine – Wikipedia,
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(Figure Presented) No preactivation of the alcohol substrates is required in allylic, propargylic, and benzylic aminations catalyzed by a combination of commercially available Bi(OTf)3 and KPF6, mostly at room temperature (see scheme). The substitution reactions of readily accessible allylic, propargylic, and benzylic alcohols with sulfonamides, carbamates, and carboxamides give the desired amine products in up to 99% yield.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H917NO – PubChem

 

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(Chemical Equation Presented) Immobilization of copper onto modified Wang resin provided a polymer-supported copper catalyst, which is effective in cross-coupling reactions between N- or O-containing substrates and arylboronic acids. The copper catalyst is air stable and can be recycled with minimal loss of activity.

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N-Acylethanolamine-hydrolyzing acid amidase (NAAA) is a lysosomal enzyme that catalyzes the hydrolysis of endogenous fatty acid ethanolamides (FAEs), such as N-palmitoylethanolamide (PEA). PEA exhibits anti-inflammatory and analgesic activities by engaging peroxisome proliferator-activated receptor alpha (PPAR-alpha). Preventing PEA degradation by inhibition of NAAA has been proposed as a novel strategy for the treatment of inflammation and pain. In the present study, we reported the discovery of the oxazolidone derivative as a novel scaffold for NAAA inhibitors, and studied the structure-activity relationship (SAR) by modification of the side chain and terminal lipophilic substituents. The results showed that the link chain length of C5, straight and saturated linkages were the preferred shape patterns for NAAA inhibition. Several nanomolar NAAA inhibitors were described, including 2f, 3h, 3i and 3j with IC50 values of 270 nM, 150 nM, 100 nM and 190 nM, respectively. Enzymatic degradation studies suggested that 2f inhibited NAAA in a selective, noncompetitive and reversible pattern. Moreover, 2f showed high anti-inflammatory and analgesic activities after systemic and oral administration.

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Oxazolidine – Wikipedia,
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We have evaluated various achiral templates (1a-g, 10, and 16) in conjunction with chiral Lewis acids in the conjugate addition of nucleophilic radicals to alpha-methacrylates followed by enantioselective H-atom transfer. Of these, a novel naphthosultam template (10) gave high enantioselectivity in the H-atomtransfer reactions with ee’s up to 90%. A chiral Lewis acid derived from MgBr2 and bisoxazoline (2) gave the highest selectivity in the enantioselective hydrogen-atom-transfer reactions. Non-C2 symmetric oxazolines (20-25) have also been examined as ligands, and of these, compound 25 gave optimal results (87% yield and 80% ee). Insights into rotamer control in alpha-substituted acrylates and the critical role of the tetrahedral sulfone moiety in realizing high selectivity are discussed.

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Oxazolidine – Wikipedia,
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Figure presented A Cu-catalyzed aerobic oxidative amidation of propiolic acids via decarboxylation under air has been developed. Only carbon dioxide is produced as byproduct in this approach. The use of air as oxidant makes this method more useful and easy to handle.

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Oxazolidine – Wikipedia,
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The 1H and 13C NMR spectra carried out on (where for R = H, X = NH, NMe, NEt, CH2, S, O; for R = Me, X = NMe, CH2; for R = Et, X = NEt) are reported.The comparison of these results with those obtained for the thionic and selonic isologues shows that sulphur and selenium have a greater deshielding effect on the ring than oxygen.The resonance of the carbons not involved in the ? system have been correlated with the ? charges calculated by the DEL RE method.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H408NO – PubChem