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The reaction of cyclic thioimidates with active methylene compounds in the presence of acetic acid anhydride was studied. In case of six- and seven-membered derivatives the reaction proceeded via substitution of thiomethoxy group affording cyclic enamines. In case of five-membered derivatives the reaction proceeded via opening of the thioimidate ring affording functionalized aminopropane derivatives.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H990NO – PubChem

 

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A highly efficient, two-step, one-pot synthetic strategy for amides and peptides was developed by employing ynamides as novel coupling reagents under extremely mild reaction conditions. The ynamides not only are effective for simple amide and dipeptide synthesis but can also be used for peptide segment condensation. Importantly, no racemization was detected during the activation of chiral carboxylic acids. Excellent amidation selectivity toward amino groups in the presence of -OH, -SH, -CONH2, ArNH2, and the NH of indole was observed, making the protection of these functional groups unnecessary in amide and peptide synthesis.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H621NO – PubChem

 

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Studies on the alkylation of enolates derived from a range of N-acyl-5,5-dimethyloxazolidin-2-ones and N-acyl-5,5-diphenyloxazolidin-2-ones reveal that high yields and high diastereoselectivities are best obtained when homochiral 4-isopropyl-5,5-dimethyloxazolidin-2-one is employed as a chiral auxiliary.

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Oxazolidine – Wikipedia,
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Provided are a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2, as well as a prophylactic/therapeutic drug for autoimmune diseases or osteoarthritis. An amide derivative represented by the following formula (I) wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof.

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Oxazolidine – Wikipedia,
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We developed conditions to carry out the first ‘one-pot’ Ullmann-Finkelstein-Ullmann multicomponent reaction reported. This reaction allows the one-pot synthesis of dissymmetrical para-disubstituted benzene scaffold from 1-bromo-4-iodobenzene and two N-nucleophiles. CuI/N,N?-dimethyl-cyclohexane-1,2-diamine was used as a catalyst/ligand couple, K3PO4 as a base and the reaction was performed in dioxane.

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Oxazolidine – Wikipedia,
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A one-pot approach using a subsequent Cu(II)/Cu(I) catalysis and a highly diastereodivergent three-component reaction allow an easy access to various aryl-pyrrolo-tetrahydrocarbazoles with the control of up to four variable fragments and two different diastereoselectivities.

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Oxazolidine – Wikipedia,
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Condensation of malononitrile, ethylcyanacetate and isopropylidene malonate with various O-ethyl cyclic carbamates leads to alpha-(tetrahydroxazole-1,3-ylidene-2) and alpha-(tetrahydroxazine-1,3-ylidene-2) malononitriles, ethylcyanacetates and isopropylidene malonates.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H631NO – PubChem

 

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 497-25-6, name is Oxazolidin-2-one, introducing its new discovery. SDS of cas: 497-25-6

The preparation method comprises the following steps. recrystallizing the crude carbamastatin crude product through an organic solvent, wherein the organic solvent is mixed solvent, of an alcohol solvent and water; the alcohol solvent is preferably selected from methanol, ethanol or isopropanol, and a high-purity carbamazine,can be prepared by the method. (by machine translation)

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Oxazolidine – Wikipedia,
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Hydroamination and hydrothiolation are the most efficient and completely atom-economical process to construct important enamine and vinyl sulfide intermediates in pharmaceutical and organic chemistry. The cyclic trimeric phosphazene base (CTPB) showed great catalytic activity for the anti-Markovnikov stereoselective hydroamination and hydrothiolation of alkynes in good to excellent yields. A broad substrate scope of alkynes and nucleophiles was demonstrated, including aryl and heteroaryl alkynes, terminal and internal alkynes, different N-heterocycles, thiols and thiophenols. This versatile and cost-efficient approach with good stereoselectivity and excellent functional group tolerance provided new opportunity for the organocatalyzed hydrofunctionalization of alkynes.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1206NO – PubChem

 

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(Chemical Equation Presented) The Midas touch: 1,3-Dienes undergo hydroamination with carbamates and sulfonamides in the presence of Ph 3PAuOTf catalyst under mild conditions (see scheme). The carbobenzyloxy (Cbz) group is readily removed from the product, and the reaction is thus an efficient method to prepare allylic amines.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H376NO – PubChem