Discovery of Oxazolidin-2-one

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497-25-6, Name is Oxazolidin-2-one, belongs to oxazolidine compound, is a common compound. Formula: C3H5NO2In an article, once mentioned the new application about 497-25-6.

The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H27NO – PubChem

 

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Chemistry is traditionally divided into organic and inorganic chemistry. SDS of cas: 497-25-6, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 497-25-6

Piperazinyl oxoalkyl tetrahydroisoquinolines and related analogues of the Formula: are provided, in which variables are as described herein. Such compounds may be used to modulate ligand binding to histamine H3 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) and other disorders in humans, domesticated companion animals and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting histamine H3 receptors (e.g., receptor localization studies).

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H46NO – PubChem

 

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Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 497-25-6. In my other articles, you can also check out more blogs about 497-25-6

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A flexible, modular ynamide synthesis is reported that uses trichloroethene as an inexpensive two carbon synthon. A wide range of amides and electrophiles can be converted to the corresponding ynamides, importantly including acyclic carbamates, hindered amides, and aryl amides. This method thus overcomes many of the limitations of other approaches to this useful functionality. This journal is

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H789NO – PubChem

 

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, HPLC of Formula: C3H5NO2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2

Three different protocols for the syntheses of hydroxyalkylnitramines are presented and compared. Safety issues regarding the synthesis of nitramines are also discussed.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H309NO – PubChem

 

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Application of 497-25-6, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 497-25-6, Oxazolidin-2-one, introducing its new discovery.

A series of novel 3-substituted-1-[5-methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-1-trans-propenes in order to improve the in vitro and in vivo activity of our prototype 3-[4-(3-chlorophenyl)-1-piperazinyl]-1-[5-methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-1-trans-propene (2) were synthesized and evaluated by assays of growth inhibition against several tumor cell lines in vitro and antitumor activity against some tumor models when dosed both intraperitoneally and orally in vivo. Compounds 7a and 7e, the 3,5-difluorophenyl and 3,5-dichlorophenyl analogues of 2, respectively, showed significantly more potent cytotoxicity than 2 in vitro and potent antitumor activities without causing decrease of body temperature related to side effects.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H852NO – PubChem

 

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497-25-6, Name is Oxazolidin-2-one, belongs to oxazolidine compound, is a common compound. category: oxazolidineIn an article, once mentioned the new application about 497-25-6.

A concise, one-pot route to oxazoles and furocoumarins has been reported. The key step in this transformation involves in situ generation of N-acyliminium ion (NAI) precursor under catalyst and solvent-free conditions and their further transformations promoted by superacid in the same pot. We have also presented the experimental evidence for the involvement of proto-solvated novel exocyclic N-acyliminium ion. Further, the UV-visible and fluorescence studies revealed that few of the compounds reported here exhibited emission of blue light upon irradiation in EtOH in the region of 404-422 nm.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H324NO – PubChem

 

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This work presents the characterization of 5-[(3,5-dimethylphenoxy)methyl]-1,3-oxazolidin-2-one (metaxalone) by DFT calculations and spectral techniques. The spectral analysis was carried out by using FT-IR and FT-Raman and 13C and 1H nuclear magnetic resonance (NMR) techniques. The FT-IR and FT-Raman spectrum were recorded in the range of 4000 to 400cm-1 and 4000 to 50cm-1 respectively. The over estimations of the calculated harmonic wavenumbers were efficiently corrected by the aid of a specific scaling procedure. 13C and 1H NMR chemical shifts of the molecule were calculated using gauge independent atomic orbital method (GIAO) and were compared with the experimental results. The molecular structure, fundamental vibrational frequencies and electronic structure calculations are carried out by density functional theory (DFT) method and B3LYP/ 6-311++G(d,p) basis set. Frontier molecular orbital energies, global reactivity descriptors and molecular electrostatic potential (MEP) were estimated. The thermodynamic properties at different temperatures were calculated revealing the correlations between standard heat capacities, entropy and enthalpy changes with temperatures.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H360NO – PubChem

 

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The present invention provides compounds of Formula (I) and (II) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H19NO – PubChem

 

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An improved strategy, which uses transition metals as effective catalyst in the presence of Me3SiCl, has been developed for the conjugate addition of chalcones with unactivated weakly nucleophilic carbamates.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1153NO – PubChem

 

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Synthetic Route of 497-25-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2. In a article,once mentioned of 497-25-6

Biphasic oxidative cyclocarbonylation of beta-aminoalcohols and 2-aminophenol to synthesize corresponding 2-oxazolidinones were investigated in the presence of ionic liquid stabilized Pd(phen)Cl2 complex. Catalytic comparison results showed that, 1-butyl-3-methyl-imidazolium iodide salts (BMImI) can serve simultaneously as a specific stabilizer to protect the transition metal complex against deactivation, a promoter to increase the catalytic performance and a reaction medium to recycle the catalyst with unprecedented TOF value.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H734NO – PubChem