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Mercury(II) acetate reacts with 2-oxazolidone (1,3-oxazolidin-2-one, C3H5NO2) in methanol to produce (L = C3H4NO2, the anion of 2-oxazolidone).An X-ray diffraction study has shown that the Hg atom binds to the ring nitrogen atom with a near linear N-Hg-N geometry.There are two HgL2 groups in the asymmetric unit which are orthogonal to one another and linked via pairs of Hg…O interactions to form dimers.These bind to neighbouring units via weaker Hg-O interactions to form a one-dimensional chain polymer.When yttrium or lanthanide(III) nitrates are added to the reaction an isostructural series of compounds of formula <(Hg2L4M(NO3)3)n>, where M = La-Yb or Y, is obtained.A representative member of this group, <(Hg2L4Gd(NO3)3)n>, was studied by single-crystal X-ray diffraction methods.This forms a two-dimensional polymeric array comprising two sizes of metallamacrocyclic rings (16- and 48-membered) fused together, with the gadolinium(III) ion surrounded by nine oxygen atoms in a trigonal tricapped-prismatic arrangement.The IR, UV/VIS reflectance, EPR and solid-state NMR spectroscopic properties of these complexes and, where appropriate, those of and are reported.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H401NO – PubChem

 

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Carbon dioxide (CO2), a well-known greenhouse gas, is also a nontoxic, readily accessible, and renewable one-carbon (C1) source. However, owing to its thermodynamic stability and kinetic inertness, the efficient utilization of CO2 is challenging. Much effort has been devoted to achieving efficient and selective organic transformations of CO2. Recently, the synthesis of important oxazolidin-2-ones from unsaturated amines by using CO2 has attracted much attention and been heavily studied. This Focus Review presents recent advances in this area by using homogenous catalysis. The cyclization of amines that contain alkynes, alkenes, and allenes with CO2 is discussed, and possible reaction mechanisms and applications of these transformations are also described.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H1204NO – PubChem

 

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The present invention relates to combination therapies comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.

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Oxazolidine – Wikipedia,
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The invention is a process for the preparation of 2-oxazolidinones which comprises contacting a 2-hydroxyalkyl carbamate with an alkylene oxide or alkylene carbonate in the presence of a catalytic amount of a quaternary ammonium halide, quaternary phosphonium halide, a group I metal carbonate, hydroxide, oxide or halide, or a group II metal carbonate, hydroxide, oxide or halide under conditions such that a 2-oxazolidinone is prepared.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H70NO – PubChem

 

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The three-component aminoallylation reaction of the activated olefins 2 with the phthalimide 1a and allyl chloride proceeded very smoothly in the presence of Pd2dba3·CHCl3 (5 mol %)/P(4-FC6H4)3 (40 mol %) and Cs2CO3 (3 equiv against 2) in dichloromethane at room temperature to give the corresponding aminoallylated products, N-pent-4-enylphthalimides 3, in 58-99% yields. The reaction of oxazolidinone 1b also proceeded very smoothly to give N-(2,2-dicyano-1-phenylpent-4-enyl)-oxazolidinone in a quantitative yield; however, the Tsuji-Trost-type allylation products 4 were obtained in the case of dibenzylamine, N-tosylaniline, and pyrrolidin-2-one. Further, 2 underwent cycloaddition with N-tosylvinylaziridine 9a in the presence of Pd2dba3·CHCl3 (5 mol %)/P(4-FC6H4)3 (40 mol %) in THF at room temperature, giving the corresponding pyrrolidines 11 in 69-99% yields.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H310NO – PubChem

 

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A new practical method for the N-acylation of amides is described. Acylation of various amides with acid anhydrides in the presence of MgBr2·OEt2 gave the corresponding N-acylamides in good to moderate yields. The present method is applicable to amides that are labile to acids or bases.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1162NO – PubChem

 

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For the first time, anodic methoxylation of 2-oxazolidinone was investigated on boron doped diamond (BDD) in CH3OHH 2SO4 medium. Voltammetric studies reveal that the 2-oxazolidinone gets oxidised at a potential of 1.5 V vs. SCE on the BDD, whereas on the graphite, the anodic oxidation takes place in the potential region of methanol oxidation. Galvanostatic electrolysis results in the formation of 4-methoxy-2-oxazolidinone (MOD) as a single product in high yield on the BDD and multiple products, along with MOD on the graphite. Generation of methoxy radical on the BDD was confirmed by Electron Spin Resonance (ESR) spectroscopy.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H955NO – PubChem

 

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The copper-catalyzed N-arylation of amides, the Goldberg reaction, usually requires drastic reaction conditions and produces only moderate yields of the desired products.Much better results can be achieved by modifying the reaction conditions.We used copper on silica as a catalyst and potassium acetate as a base and continuously removed the resulting acetic acid from the reaction mixture.In this way we gained high, in some cases nearly quantitative yields of the arylated or heteroarylated products.

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Oxazolidine – Wikipedia,
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Herein we report our full investigation into the calcium catalyzed generation and trapping of N-acyliminium ions from readily available 3-hydroxyisoindolinones. We have successfully employed a range of traditional nucleophiles including carbon, nitrogen, and sulfur containing reactive partners. The reaction is tolerant to a wide range of functionalities and provides high value scaffolds in good to excellent yields.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H338NO – PubChem

 

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New mercaptan-terminated polythiourethanes were applied as curing agents for epoxy resin. The formulation studied consisted of a diglycidyl ether of bisphenol A epoxy resin, polythiourethane curing agent accelerated with primary or tertiary amine. The coating performance of the resins was tested by measurements of scratch resistance, pencil hardness, flexibility, adhesion and chemical resistance. The results show better properties of the polythiourethane-cured resin compared to standard epoxy formulation. It is observed that evaluation of the physico-mechanical and chemical resistance performance shows better results with the increased loading of polythiourethane hardener. In addition, polythiourethane hardeners revealed high reactivity toward curing of epoxy resins at low-temperature conditions (-10 C). Polythiourethane-cured epoxy resins, thus stand as an effective surface coating material where high performance is needed in terms of physico-mechanical properties as well as chemical resistance.

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Reference:
Oxazolidine – Wikipedia,
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