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497-25-6, Name is Oxazolidin-2-one, belongs to oxazolidine compound, is a common compound. SDS of cas: 497-25-6In an article, once mentioned the new application about 497-25-6.

A stable dispersion of polysiloxane thermoplastic polyurethane (TPU) particles in an epoxy resin matrix was achieved via epoxy ring opening with the isocyanate groups of urethane prepolymer to form an oxazolidone. The effects of the structure and molecular weight of the polysiloxane TPU in reducing the stress of electronic encapsulants were investigated. The mechanical and dynamic viscoelastic properties of polysiloxane TPU-modified epoxy networks were also studied. A phase-separated structure was observed via scanning electron microscopy. The dispersed polysiloxane TPU rubbers effectively reduce the stress of cured epoxy resins by reducing the flexural modulus and the coefficient of thermal expansion, while the glass transition temperature is increased because of the formation of the rigid oxazolidone structure. Electronic devices encapsulated with the polysiloxane TPU-modified epoxy moulding compounds have exhibited an excellent resistance in the thermal shock cycling test and have resulted in an extended device used life. Copyright

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H611NO – PubChem

 

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Flash vacuum pyrolysis (FVP) of azides is an extremely valuable method of generating nitrenes and studying their thermal rearrangements. The nitrenes can in many cases be isolated in low-temperature matrices and observed spectroscopically. NH and methyl, alkyl, aralkyl, vinyl, cyano, aryl and N-heteroaryl, acyl, carbamoyl, alkoxycarbonyl, imidoyl, boryl, silyl, phosphonyl, and sulfonyl nitrenes are included. FVP of triazoloazines generates diazomethylazines and azinylcarbenes, which often rearrange to the energetically more stable arylnitrenes. N2 elimination from monocyclic 1,2,3-triazoles can generate iminocarbenes, 1H-azirines, ketenimines, and cyclization products, and 1,2,4-triazoles are precursors of nitrile ylides. Benzotriazoles are preparatively useful precursors of cyanocyclopentadienes, carbazoles, and aza-analogues. FVP of 5-aryltetrazoles can result in double N2 elimination with formation of arylcarbenes or of heteroarylcarbenes, which again rearrange to arylnitrenes. Many 5-substituted and 2,5-disubstituted tetrazoles are excellent precursors of nitrile imines (propargylic, allenic, or carbenic), which are isolable at low temperatures in some cases (e.g., aryl- and silylnitrile imines) or rearrange to carbodiimides. 1,5-Disubstituted tetrazoles are precursors of imidoylnitrenes, which also rearrange to carbodiimides or add intramolecularly to aryl substituents to yield indazoles and related compounds. Where relevant for the mechanistic understanding, pyrolysis under flow conditions or in solution or the solid state will be mentioned. Results of photolysis reactions and computational chemistry complementing the FVP results will also be mentioned in several places.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1130NO – PubChem

 

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CO2 capture and storage are quite a promising approach to limit greenhouse gas emission. However CO2 capture process relies on the use of amine solutions which are likely to degrade and produce potentially harmful compounds. To ensure an environmental acceptance and to understand this degradation, analytical methods are needed to identify and quantify as many as possible of these products. In our study, monoethanolamine was used as a model compound for CO2 capture. Therefore an analytical strategy was developed to provide the most exhaustive list of degradation products. It was based on the complementarity between liquid and gas chromatography coupled with various mass spectrometry ionization and detection modes.. This analytical strategy enabled the identification of 59 degradation products in pilot plant samples, but 26 of which were never reported. It provides also key information to develop quantification methods for pilot or industrial plant monitoring.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H461NO – PubChem

 

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 497-25-6, name is Oxazolidin-2-one, introducing its new discovery. HPLC of Formula: C3H5NO2

The equilibrium C-H bond acidities of three cyclic carboxylic esters wherein the alkoxycarbonyl group is locked into an E conformation have been shown to be about 4 pKHA units greater than those of their acyclic analogues.Also, replacement of an alpha-methylene group in 2-indanone by an oxygen atom to form a cyclic ester of this type has been shown to cause an acidity increase of a comparable magnitude.These acidity increases are roughly one-half that observed for Meldrum’s acid, a similarly constituted cyclic diester, relative to that of an acyclic analogue, dimethyl malonate.A similar increase in the N-H acidity of an acyclic carbamate was found to occur when its alkoxycarbonyl moiety was locked into a five-membered (2-oxazolidone) ring.These structural changes were found to cause little or no change in the BDEs of the acidic C-H or N-H bonds in these esters or carbamates.On the other hand, introduction of a C=C bond into 2-oxazolidone caused a 15 kcal/mol decrease in BDE.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1203NO – PubChem

 

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The present invention relates to a method for producing a cured composition, which has at least one oxazolidinone ring and at least one isocyanurate ring and is crosslinked thereby, starting from a liquid reaction mixture comprising: (a) at least one liquid, aromatic epoxy resin; (b) at least one liquid, aromatic polyisocyanate; and (c) a catalyst composition; relative to the at least one polyisocyanate, the at least one epoxy resin is used in amounts such that the molar equivalent ratio of epoxide groups to isocyanate groups is at least 0.4; and curing the reaction mixture to give a cured polymer composition comprising at least one oxazolidinone ring and at least one isocyanurate ring, and also to the cured compositions obtainable by these methods.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H121NO – PubChem

 

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The first use of enamide substrates in an Ireland-Claisen [3,3]-sigmatropic rearrangement reaction is presented as a novel route to complex beta2,3-amino acids.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1180NO – PubChem

 

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A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R4 have the significance given in claim 1, can be used as a modulator of AMPK

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H54NO – PubChem

 

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Background: Multiple drug resistance (MDR) in staphylococci, including resistance to the semi-synthetic penicillinase-resistant penicillins such as meticillin, is a problem of global proportions that presents serious challenges to the successful treatment of staphylococcal infections of companion animals. Objectives: The objective of this document is to provide harmonized recommendations for the diagnosis, prevention and treatment of meticillin-resistant staphylococcal infections in dogs and cats. Methods: The authors served as a Guideline Panel (GP) and reviewed the literature available prior to September 2016. The GP prepared a detailed literature review and made recommendations on selected topics. The World Association of Veterinary Dermatology (WAVD) provided guidance and oversight for this process. A draft of the document was presented at the 8th World Congress of Veterinary Dermatology (May 2016) and was then made available via the World Wide Web to the member organizations of the WAVD for a period of three months. Comments were solicited and posted to the GP electronically. Responses were incorporated by the GP into the final document. Conclusions: Adherence to guidelines for the diagnosis, laboratory reporting, judicious therapy (including restriction of use policies for certain antimicrobial drugs), personal hygiene, and environmental cleaning and disinfection may help to mitigate the progressive development and dissemination of MDR staphylococci.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H835NO – PubChem

 

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The present invention is directed to tricyclic compounds of formula (I), pharmaceutically acceptable compositions comprising compounds of the invention and said compositions for use in methods for the treatment of various disorders in particular cancer.

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Oxazolidine – Wikipedia,
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A new azithromycin-based series of antibacterial macrolones is reported, which features the use of a 4?-ester linked glycin for tethering the quinolone side chain to the macrolide scaffold. Among the analogs prepared, compounds 9e and 22f with a quinolon-6-yl moiety were found to have potent and well-balanced activity against clinically important respiratory tract pathogens, including erythromycin-susceptible and MLSB resistant strains of Streptococcus pneumoniae, Streptococcus pyogenes, and Haemophilus influenzae. In addition, potential lead compounds 9e and 22f demonstrated outstanding levels of activity against Moraxella catarrhalis and inducibly MLSB resistant Staphylococcus aureus. The best member of this series 22f rivals or exceeds, in potency, some of the most active ketolide antibacterial agents known today, such as telithromycin and cethromycin.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H886NO – PubChem