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A comprehensive overview on methods applied for syntheses of beta-amino-alpha-trifluoromethyl alcohols, including stereocontrolled variants, is presented. In addition, reported cases of the exploration of beta-amino-alpha-trifluoromethyl alcohols for the preparation of trifluoromethylated peptidomimetics and other biologically active, fluorinated compounds are discussed. Attractive opportunities for their applications as organocatalysts are also presented.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H826NO – PubChem

 

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Catalytic asymmetric Diels-Alder reactions of N-allenoyloxazolidinones were investigated. Various chiral metal-bis(oxazoline) and metal-pyridinebis(oxazoline) complexes were screened. Cu(SbF6)2(H2O)2(t-BuBox) was found to be the most effective catalyst, giving the product in high yield, enantioselectivity, and endo:exo selectivity. The relative reactivity between N-allenoyloxazolidinones and N-alkenoyloxazolidinones was also investigated. A model for stereoinduction was proposed to account for the enantioselectivity and endo:exo selectivity.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H776NO – PubChem

 

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One of the oldest and most widely used commercial enzyme inhibitors is aspirin, COA of Formula: C3H5NO2, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 497-25-6

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, COA of Formula: C3H5NO2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2

The invention pertains to a process for manufacturing a mixture of straight-chain higher ethyleneamines and non-straight-chain higher ethyleneamines selected from branched higher ethyleneamines and cyclic higher ethyleneamines, or the urea derivatives thereof, comprising the step of reacting amine-functional compound with ethanolamine-functional compound in the presence of a carbon oxide delivering agent, wherein a) amine-functional compound comprising a combination of straight-chain amine- functional compound and non-straight-chain amine-functional compound is reacted with straight-chain ethanolamine-functional compound, or b) straight-chain amine-functional compound is reacted with ethanolamine-functional compound comprising a combination of straight-chain ethanolamine-functional compound and non-straight-chain ethanolamine-functional compound, or c) amine-functional compound comprising a combinationof straight-chain amine-functional compound and non-straight-chain amine-functional compound is reacted with ethanolamine-functional compound comprising a combination of straight-chain ethanolamine-functional compound and non-straight-chain ethanolamine-functional compound. It has been found that the process according to the invention makes it possible to prepare tailor-made mixtures of straight-chain and non-straight-chain higher ethyleneamines, or urea derivatives thereof.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H240NO – PubChem

 

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Related Products of 497-25-6, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 497-25-6, Oxazolidin-2-one, introducing its new discovery.

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing said compound, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition comprising said compound.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H39NO – PubChem

 

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1,2-Diaryl-substituted imidazolidines proved to be ring-chain tautomeric mixtures in CDCl3 at 300 K. Both 1- and 2-aryl groups exerted significant electronic effect on the tautomeric equilibria, which could be described by the equation log KX=rho?+ + log KX=H.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H559NO – PubChem

 

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CO2 capture with alkanolamines has been in use since 1930, where MEA is the most studied absorbent for post-combustion. In order to prevent degradation, it is important to understand the degradation mechanisms, which in turn requires knowledge of both stoichiometry and kinetics of the reactions. The stability of the degradation products is a starting point when exploring possible mechanisms, and can be determined from the Gibbs free energy of the net reaction. In the present work, quantum mechanical calculations and continuum solvation models are used to calculate the reaction energy for different oxidative degradation reactions and to verify the suggested mechanism for thermal degradation of MEA with CO2. The suggested total reaction mechanisms for thermal degradation with CO2 were found to be energetically favorable, and oxalic acid, oxalamide and 1-(2-hydroxyethyl)- imidazole (HEI) were found to be of the most probable oxidative degradation products.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1090NO – PubChem

 

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Mild, efficient, copper-catalyzed N-arylation procedures for nitrogen heterocycles, amides, carbamates, and C-arylation procedures for malonic acid derivatives have been developed that afford high yields of arylated products with excellent selectivity. The N-arylation of imidazole with aryl bromides or iodides was found to be greatly accelerated by inexpensive, air-stable catalyst systems, combining catalytic copper salts or oxides with a set of structurally simple chelating ligands. The reaction was shown to be compatible with a broad range of aryl halides, encompassing sterically hindered, electron-poor, and electron-rich ones, providing the arylated products under particularly mild conditions (50-82C). The lower limit in ligand and catalyst loading and the scope of Ullmann-type condensations catalyzed by complexes bearing those ligands with respect to the nucleophile class have also been investigated. Chelating Schiff base Chxn-Py-Al (1c) generates a remarkably general copper catalyst for N-arylation of pyrrole, indole, 1,2,4-triazole, amides, and carbamates; and C-arylation of diethyl malonate, ethyl cyanoacetate, and malononitrile with aryl iodides under mild conditions (50-82C). The new method reported here is the most successful to date with regard to Ullmann-type arylation of some of these nucleophiles.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H457NO – PubChem

 

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 497-25-6, name is Oxazolidin-2-one, introducing its new discovery. Application In Synthesis of Oxazolidin-2-one

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H50NO – PubChem

 

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Quantum dot (QD) nanoparticles (NPs) are increasingly used as highly valuable fluorescent biomarkers and as sensitive (bio)chemical probes. Interestingly, if certain metal impurities are incorporated during the NPs synthesis, phosphorescent QDs with analytical potential can be obtained.We report here the synthesis of colloidal manganese-doped ZnS nanoparticles which have been surface-modified with l-cysteine that exhibit an intense room temperature phosphorescence (RTP) emission in aqueous media even in the presence of dissolved oxygen (i.e. sample deoxygenation is not needed). An exhaustive RTP photoluminescent and morphological characterization of the synthesized QDs and their potential for development of phosphorescent analytical methodologies is described. Application to analytical control of acetone (” model analyte” from the ketones family) in water and urine samples is carried out by measuring the QDs phosphorescence quenching rate.The observed results showed a high selectivity of Mn2+-doped ZnS QDs towards acetone. The linear range of the developed methodology turned out to be at least up to 600mgL-1 with a detection limit (DL) for acetone dissolved in aqueous medium of 0.2mgL-1. The developed methodology was finally applied for acetone determination in different spiked water and urine samples, and the recoveries fall in the range of 93-107%.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1018NO – PubChem

 

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A dienolate aldol/bromolactonization sequence has been used to demonstrate a new stereocontrolled route to protected alpha-(1-hydroxyalkyl) 2-oxetanones, and thus specifically functionalized tetrahydrofurans.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H805NO – PubChem