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A bismuth(III) triflate catalyzed three-component synthesis of alpha-substituted amides starting from amides, aldehydes, and (hetero)arenes is reported. The reaction has a broad substrate scope, encompassing formaldehyde as well as aryl and alkyl aldehydes. Low catalyst loadings are required, and water is formed as the only side product. The scope and limitation of this method will be discussed.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H965NO – PubChem

 

Chemistry Milestones Of (R)-4-Benzyl-2-oxazolidinone

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Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. name: (R)-4-Benzyl-2-oxazolidinone,

The title total synthesis was achieved by employing deconjugative asymmetric alpha-sulfenylation of the chiral 3-(alpha,beta,gamma,delta-unsaturated acyl)oxazolidin-2-one with a 3,3-dimethoxypropyl methanethiosulfonate as a key step. From the biological activity assay carried out using the title compounds, it appeared evident that in vitro antibacterial and mammalian type I FAS inhibitory activity can be cleanly separated by changing not only the substituent at the C3-position but also the absolute configuration at the C5-position, and that unnatural (S)-(-)-3-demethylthiolactomycin and its congeners might be usable as selective mammalian type I FAS inhibitors.

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Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application of 147959-19-1. Introducing a new discovery about 147959-19-1, Name is (S)-tert-Butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate

There are provided novel compounds of formula (I) wherein T, X, Y and W are as defined in the specification, and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds arc inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain.

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Reference of 497-25-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2. In a Article,once mentioned of 497-25-6

Reaction between secondary amines and vinyl triflates of alpha-keto esters and imides under solvent-free condition provides a ready access to alpha,beta-diamino carboxylates.

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More research is needed about 5-(Hydroxymethyl)oxazolidin-2-one

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Azachrysenes are aromatic tetracyclic structures where one carbon atom is replaced by nitrogen in any symmetrically distinct position of the fused aromatic ring. They can be considered analogs of azasteroids, with recognized potential as drug candidates. The present review surveys the work carried out over the last three decades on the synthesis of mono-, di-, tri- and penta-azachryzene derivatives. Although a diversity of synthetic approaches were described in the literature, there are no recent review articles on this subject.

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Our Top Choice Compound: Oxazolidin-2-one

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The present application relates to novel substituted indazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recurrent bleeding in patients with or without underlying hereditary or acquired hemostatic disorders, wherein the bleeding is associated with a disease or medical intervention selected from the group consisting of heavy menstrual bleeding, postpartum hemorrhage, hemorrhagic shock, trauma, surgery, transplantation, stroke, liver diseases, hereditary angioedema, nosebleed, and synovitis and cartilage damage following hemarthrosis.

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The blend MEA/MDEA (5/25%wt.) was studied on the LEMEDES-CO2 lab-scale pilot plant, with representative conditions of post-combustion CO2 capture for power generation during 900 h. CO2 loadings were determined and showed average values of 0.12 and 0.40 respectively for the lean and rich solvents. Stability of the two amines, namely MEA and MDEA, was monitored using ionic chromatography; results did not show any significant degradation of MDEA during the campaign, in contrary to MEA which showed a significant degradation in the range of 0.03 points per day. Analytical methods involving GC?MS and IC were developed in order to identify potential degradation products in the liquid phase of the solvent. Study of the gaseous emissions? composition was also realized using sampling on different solid sorbents followed by thermal desorption and GC?MS analysis. A total of 22 compounds were listed including amines, organic acids, and pyrazines derivatives. 12 degradation products were found in the solvent itself and 11 in the treated flue gas among which MDEA, the constituent amine of the blend. A quantitative monitoring was carried out for formic and oxalic acids. Results showed concentrations reaching 500 mg/L for oxalic acid and 1400 mg/L for formic acid.

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1,6-Bis(2-oxooxazolidin-3-ylcarbonylamino)hexane (1) was prepared from 2-oxazolidinone and hexamethylenediisocyanurate using triethylenediamine as a catalyst in benzene.A TG effluent gas is collected in a cold trap and then directly injected into a GC for separation, the MS for unequivocal identification.The 13 effluent compounds from the thermal degradation of 1 were identified.

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Downstream Synthetic Route Of (S)-4-Phenyl-3-propionyloxazolidin-2-one

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A novel acid-promoted rearrangement is disclosed. In the previously unknown transformation, an allyl group migrated to an in situ formed carbocation stabilized by an electron-rich aryl or heteroaryl group, resulting in a stereoselective intramolecular Grob fragmentation. The outcome of the rearrangement observed with an array of substrates can be satisfactorily rationalized using a working hypothesis with the aid of a six-membered transition state similar to those proposed for the anionic oxy-Cope or oxonia-Cope rearrangements, but involving only one instead of two double bonds.

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497-25-6, Modeling chemical reactions helps engineers virtually understand the chemistry, optimal size and design of the system, and how it interacts with other physics that may come into play.In a article, mentioned the application of 497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2

A pilot plant campaign was performed to study MEA degradation in CO2 capture conditions and anticipate potential degradation products emissions to the atmosphere in industrial case. Aqueous 30% wt MEA was cycled between absorption and regeneration steps during 1700 h in the presence of a synthetic flue gas containing 81% of N2, 14% of CO2, 5% of O2, 97 ppm of NO, 9 ppm of SO2 and 5 ppm of NO2. Specific methods (sampling, sample conditioning and analysis) were developed to improve degradation products identification and to provide a quantification of targeted compounds in liquid phase and above all in absorber and stripper gas effluents. Especially, trace elements were detected in liquid phase thanks to Head Space-Solid Phase MicroExtraction (HS-SPME) and liquid-liquid extraction with ChemElut cartridges and in gas phase thanks to adsorbent tubes of different type: Sep-Pak for aldehydes and ketones, Orbo 60 for N-nitrosodimethylamine, Tenax and active charcoal for non-specific adsorption. 32 degradation products were identified in liquid phase and 38 in gas phase, 17 of which for the first time, especially derivatives of pyridine and oxazolidine, 1H-pyrrole and a new nitrosamine, the N-nitroso-2-methyl-oxazolidine.

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