Category: oxazolidine

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 288-42-6, is researched, SMILESS is O1C=NC=C1, Molecular C3H3NOJournal, Article, Research Support, Non-U.S. Gov’t, Scientific Reports called Kinetics of Photo-Oxidation of Oxazole and its Substituents by Singlet Oxygen, Author is Zeinali, Nassim; Oluwoye, Ibukun; Altarawneh, Mohammednoor; Dlugogorski, Bogdan Z., the main research direction is oxazole photooxidation kinetics Diels Alder reaction mechanism activation energy.Safety of Oxazole.

Oxazole has critical roles not only in heterocycle (bio)chem. research, but also as the backbone of many active natural and medicinal species. These diverse and specialised functions can be attributed to the unique physicochem. properties of oxazole. This contribution investigates the reaction of oxazole and its derivatives with singlet oxygen, employing d. functional theory DFT-B3LYP calculations The absence of allylic hydrogen in oxazole eliminates the ene-mode addition of singlet oxygen to the aromatic ring. Therefore, the primary reaction pathway constitutes the [4 + 2]-cycloaddition of singlet oxygen to oxazole ring, favoring an energetically accessible corridor of 57 kJ/mol to produce imino-anhydride which is postulated to convert to triamide end-product in subsequent steps. The pseudo-first-order reaction rate for substituted oxazole (e.g., 4-methyl-2,5-diphenyloxazole, 1.14 x 106 M-1 s-1) appears slightly higher than that of unsubstituted oxazole (0.94 x 106 M-1 s-1) considering the same initial concentration of the species at 300 K, due to the electronic effect of the functional groups. The global reactivity descriptors have justified the relative influence of the functional groups along with their resp. physiochem. properties.

There are many compounds similar to this compound(288-42-6)Safety of Oxazole. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone, is researched, Molecular C12H16N2O2, CAS is 67914-60-7, about Dependence of mechanisms to thermodynamics in the electrochemical study of different electrophiles in the presence of some sulfur nucleophiles, the main research direction is electrophile isulfur nucleophile electrochem oxidation reaction mechanism.HPLC of Formula: 67914-60-7.

Abstract: Electrochem. study of different electrophiles in the presence of p-toluenesulfinic acid and 2-mercaptobenzothiazole as sulfur nucleophiles was investigated. Mechanistic study of the electrochem. reactions indicates that the electrochem. oxidation of some species in the presence of the sulfur groups has different mechanisms, but some other species in the presence of both sulfur nucleophiles have the same mechanism. To explain the reason for this difference, the computational study was used. Thermodn. investigation shows that when ΔGtot of the electrochem. oxidation of products are less than that of initial species, the electrochem. produced species can be oxidized during controlled-potential coulometry. The results of this work indicate that the computational study can be used to justify the reaction mechanisms. Cyclic voltammetry, linear sweep voltammetry, and controlled-potential coulometry were used to obtain the exptl. results. Also, by the use of BP86 level of theory and 6-31 + G(d,p) basis set, the theor. data were obtained.

There are many compounds similar to this compound(67914-60-7)HPLC of Formula: 67914-60-7. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Name: 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone, is researched, Molecular C12H16N2O2, CAS is 67914-60-7, about Synthesis and antimicrobial activity of new series of piperazine containing chalcone derivatives. Author is Kumar, J. Ranjith; Nissankararao, Srinath; Ushasri, S.; Rehaman, Sk. A..

Treatment of 1-acetyl-4-(4-hydroxyphenyl)piperazine with aromatic or substituted aromatic aldehydes in presence of methanol and potassium hydroxide, formed 3-substituted phenyl-1-(4-(4-hydroxylphenyl)piperzin-1-yl)-prop-2-en-1-one derivatives I (R = Ph, 4-ClC6H4, 4-FC6H4, etc.). These are assayed for their antibacterial activity against Bacillus pumilus, Bacillus subtilis, Escherichia coli, Proteus vulgaris and for antifungal activity against Aspergillus niger, Candida albicans strains. Antibacterial assay revealed that Bacillus subtilis and Proteus vulgaris were the most sensitive bacterial strains to compounds I (R = 4-ClC6H4, 4-FC6H4, 4-O2NC6H4, 2,4-di-MeOC6H3, 2,4-Cl2C6H3) and in the antifungal assay, compounds I (R = Ph, 4-FC6H4, 2,4-Cl2C6H3) were highly effective against Aspergillus niger when compared to other other investigated strains.

There are many compounds similar to this compound(67914-60-7)Name: 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Ghazvini, Maryam; Sheikholeslami-Farahani, Fatemeh; Hamedani, Naghmeh Faal; Shahvelayati, Ashraf Sadat; Rostami, Zohreh published the article 《Bio-Fe3O4 Magnetic Nanoparticles Promoted Green Synthesis of thioxo-1,3-Oxazole Derivatives: Study of Antimicrobial and Antioxidant Activity》. Keywords: furooxazole thioxo preparation green chem antioxidant antibacterial activity; bromo ketone isothiocyanate multicomponent reaction ferrimagnetic magnetite nanocatalyst; 2-thioxo-1; 3-oxazole; Alkyl (aryl) isothiocyanates; Alkyl bromides; Fe3O4-MNPs; Orange peel extract; antioxidant ability.They researched the compound: Ethyl 3-bromo-2-oxopropanoate( cas:70-23-5 ).SDS of cas: 70-23-5. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:70-23-5) here.

In this work, 1,3-oxazoles I (R = COOEt, 4-methoxyphenyl, 4-methylphenyl, 4-bromophenyl; R1 = t-Bu, 4-methoxyphenyl, 4-nitrophenyl; R2 = COOEt, 4-methoxyphenyl, 4-methylphenyl, 4-bromophenyl) were generated using the multicomponent reaction of α-bromo ketones R/R2C(O)CH2Br, alkyl (aryl) isothiocyanates R1N=C=S, sodium hydride and Fe3O4 MNPs in the water at room temperature in good yields. The nanoparticles generated via the biosynthesis method have potential value in different purposes, such as organic synthesis. To study the antioxidant ability of some synthesized thioxo-1,3-oxazoles I, diphenyl-picrylhydrazine (DPPH) radical trapping and power of ferric reduction testes are employed. Among the studied thioxo-1,3-oxazoles, compound I (R = R2 = COOEt; R1 = 4-nitrophenyl) have good power for radical trapping and reduction activity than the standard antioxidants such as BHT and TBHQ. In addition, the antimicrobial activity of some thioxo-1,3-oxazoles I was studied, employing the disk diffusion test on Gram-pos. bacteria and Gram-neg. bacteria. The results of the disk diffusion test showed that compounds I (R = R2 = COOEt, R1 = 4-nitrophenyl; R = R2 = COOEt, R1 = 4-methoxyphenyl; R = R2 = 4-methoxyphenyl, R1 = t-Bu; R = R2 = 4-bromophenyl R1 = 4-nitrophenyl) prevented bacterial growth. Without employing catalyst, these reactions have low yield and busy mixture The synthesis of compound I (R = R2 = COOEt; R1 = 4-methoxyphenyl) as sample reaction has a similar yield in the presence of ZnO-NPs and Fe3O4 MNPs (entry 20 and entry 30), but the removal of catalyst from the mixture of reaction after the completion of the reaction is comfortable in the presence of Fe3O4 MNPs. Some of the advantages of performing these reactions with the present procedure are to carry out these reactions in water as a green solvent and simple removal of catalyst.

There are many compounds similar to this compound(70-23-5)SDS of cas: 70-23-5. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Kavitha, Channappa N.; Jasinski, Jerry P.; Anderson, Brian J.; Yathirajan, H. S.; Kaur, Manpreet researched the compound: 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone( cas:67914-60-7 ).Application In Synthesis of 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone.They published the article 《1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethanone》 about this compound( cas:67914-60-7 ) in Acta Crystallographica, Section E: Structure Reports Online. Keywords: hydroxyphenylpiperazinylethanone crystal structure. We’ll tell you more about this compound (cas:67914-60-7).

In the title compound, C12H16N2O2, the piperazine ring has a chair conformation. The dihedral angle between the mean planes of the benzene ring and the acetyl group is 48.7 (1)°. In the crystal, mols. are linked via O-H···O hydrogen bonds, forming chains propagating along [010].

There are many compounds similar to this compound(67914-60-7)Application In Synthesis of 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Quality Control of Cupric bromide. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Cupric bromide, is researched, Molecular Br2Cu, CAS is 7789-45-9, about Colored Janus nanocylinders driven by supramolecular coassembly of donor and acceptor building blocks. Author is Choisnet, Thomas; Canevet, David; Salle, Marc; Lorthioir, Cedric; Bouteiller, Laurent; Woisel, Patrice; Niepceron, Frederick; Nicol, Erwan; Colombani, Olivier.

Janus nanocylinders exhibit nanometric dimensions, a high aspect ratio, and two faces with different chemistries (Janus character), making them potentially relevant for applications in optics, magnetism, catalysis, surface nanopatterning, or interface stabilization, but they are also very difficult to prepare by conventional strategies. In the present work, Janus nanocylinders were prepared by supramol. coassembly in water of two different polymers functionalized with complementary assembling units. The originality of our approach consists in combining charge transfer complexation between electron-rich and electron-poor units with hydrogen bonding to (1) drive the supramol. formation of one-dimensional structures (cylinders), (2) force the two polymer arms on opposite sides of the cylinders independently of their compatibility, resulting in Janus nanoparticles, and (3) detect coassembly through a color change of the solution upon mixing of the functional polymers.

Compound(7789-45-9)Quality Control of Cupric bromide received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Cupric bromide), if you are interested, you can check out my other related articles.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

COA of Formula: Br2Cu. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Cupric bromide, is researched, Molecular Br2Cu, CAS is 7789-45-9, about Layered Copper-Metallated Covalent Organic Frameworks for Huisgen Reactions. Author is Romero-Muniz, Ignacio; Albacete, Pablo; Platero-Prats, Ana E.; Zamora, Felix.

Covalent organic frameworks (COFs) are porous materials formed through condensation reactions of organic mols. via the formation of dynamic covalent bonds. Among COFs, those based on imine and β-ketoenamine linkages offer an excellent platform for binding metallic species such as copper to design efficient heterogeneous catalysts. In this work, imine- and β-ketoenamine-based COF materials were modified with catalytic copper sites following a metalation method, which favored the formation of binding amine defects. The obtained copper-metalated COF materials were tested as heterogeneous catalysts for 1,3-dipolar cycloaddition reactions, resulting in high yields and recyclability.

Compound(7789-45-9)COA of Formula: Br2Cu received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Cupric bromide), if you are interested, you can check out my other related articles.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Xu, Yuankang; Wang, Hanyu; Zhao, Jinyan; Yang, Xiaofeng; Pei, Meishan; Zhang, Guangyou; Zhang, Yanxia published the article 《A dual functional fluorescent sensor for the detection of Al3+ and Zn2+ in different solvents》. Keywords: dual functional fluorescent sensor aluminum zinc detection solvent.They researched the compound: Ethyl 3-bromo-2-oxopropanoate( cas:70-23-5 ).Application of 70-23-5. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:70-23-5) here.

(E)-N’-((2-Hydroxynaphthalen-1-yl)methylene)imidazo[2,1-b]thiazole-6-carbohydrazide (X), a new fluorescent sensor, was designed and synthesized based on imidazo[2,1-b]thiazole and 2-hydroxy-1-naphthaldehyde, which could be used to detect Al3+ in methanol buffer solution and detect Zn2+ in ethanol buffer solution with detection limits of 1.45 × 10-7 M and 1.29 × 10-8 M, resp. X showed high sensitivity and selectivity towards Al3+ and Zn2+ in the presence of other metal ions. The fluorescence intensity of X was reversible even after six cycles with the sequentially alternative addition of metal ions (Al3+ and Zn2+) and PPi, showing an efficient off-on-off fluorescence behavior. The complexation ratio of X to Al3+ and Zn2+ was 1 : 1, which was proved by mass spectrometry and the B-H equation. The binding mode and sensing mechanism of X with metal ions (Al3+ and Zn2+) were verified by DFT/TDDFT calculations using Gaussian 09 based on the B3LYP/6-31G(d) basis set.

Compound(70-23-5)Application of 70-23-5 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Ethyl 3-bromo-2-oxopropanoate), if you are interested, you can check out my other related articles.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Porter, A. E. A.; Sammes, Peter G. published an article about the compound: 6-Hydroxy-2-methylpyrimidin-4(3H)-one( cas:1194-22-5,SMILESS:CC1=NC(=CC(N1)=O)O ).Computed Properties of C5H6N2O2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1194-22-5) through the article.

The adducts I and II are prepared from III and IV and the dienophiles, MeO2CCCCO2Me and norbornadiene, resp. Brevianamide A, previously isolated from Penicillium brevi-compactum [Birch, J. A. and Wright, J. J. (1969)], may be obtained in nature by a similar process.

Here is just a brief introduction to this compound(1194-22-5)Computed Properties of C5H6N2O2, more information about the compound(6-Hydroxy-2-methylpyrimidin-4(3H)-one) is in the article, you can click the link below.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

An, Seungchan; Kim, Gyudong; Kim, Hyun Jin; Ahn, Sungjin; Kim, Hyun Young; Ko, Hyejin; Hyun, Young Eum; Nguyen, Mai; Jeong, Juri; Liu, Zijing; Han, Jinhe; Choi, Hongseok; Yu, Jinha; Kim, Ji Won; Lee, Hyuk Woo; Jacobson, Kenneth A.; Cho, Won Jea; Kim, Young-Mi; Kang, Keon Wook; Noh, Minsoo; Jeong, Lak Shin published an article about the compound: 2,6-Dichloropurine( cas:5451-40-1,SMILESS:C2=NC1=C(C(=NC(=N1)Cl)Cl)[NH]2 ).Formula: C5H2Cl2N4. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:5451-40-1) through the article.

Following our report that A3 adenosine receptor (AR) antagonist 1 exhibited a polypharmacol. profile as a dual modulator of peroxisome proliferator-activated receptor (PPAR)γ/δ, we discovered a new template, 1′-homologated adenosine analogs 4a-4t, as dual PPARγ/δ modulators without AR binding. Removal of binding affinity to A3AR was achieved by 1′-homologation, and PPARγ/δ dual modulation was derived from the structural similarity between the target nucleosides and PPAR modulator drug, rosiglitazone. All the final nucleosides were devoid of AR-binding affinity and exhibited high binding affinities to PPARγ/δ but lacked PPARα binding. 2-Cl derivatives exhibited dual receptor-binding affinity to PPARγ/δ, which was absent for the corresponding 2-H derivatives 2-Propynyl substitution prevented PPARδ-binding affinity but preserved PPARγ affinity, indicating that the C2 position defines a pharmacophore for selective PPARγ ligand designs. PPARγ/δ dual modulators functioning as both PPARγ partial agonists and PPARδ antagonists promoted adiponectin production, suggesting their therapeutic potential against hypoadiponectinemia-associated cancer and metabolic diseases.

Here is just a brief introduction to this compound(5451-40-1)Formula: C5H2Cl2N4, more information about the compound(2,6-Dichloropurine) is in the article, you can click the link below.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem