Electric Literature of 22625-57-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 22625-57-6, Name is 5-(Chloromethyl)oxazolidin-2-one, molecular formula is C4H6ClNO2. In a Article,once mentioned of 22625-57-6
In the present study, in order to synthesize broad-spectrum antibacterial agents, we coupled both the oxazolidinone and novel thiophene chalcone derivatives by using Buchwald’s protocol under ultrasound irradiation. All the newly synthesized 20 oxazolidinone-thiophene chalcone hybrid compounds were characterized by IR,1HNMR and Mass spectral analysis and evaluated for in vitro antibacterial and antifungal activities. Antibacterial and antifungal activities were tested using the serial dilution method. The test compounds 7e to 7g exhibited very high activities at 3.125 mug/ml when compared to the standard drug linezolid and were as other compounds showed moderate to weak activities. In case of antifungal activities, the test compounds 7e to 7g, 7i,7j, and 7m to 7o exhibited moderate activities compared to the standard fluconazole, whereas the rest of the compounds showed weak activities against tested fungal strains. The binding mode analysis of the test compounds 7e to 7g were investigated by the docking studies using Glide 6.6., inside the active site of peptidyl transferase center of E.coli ribosome (PDB ID: 2AW4), revealed that the experimental results were comparable to that of co-crystallized ligand linezolid.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 22625-57-6. In my other articles, you can also check out more blogs about 22625-57-6
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1448NO – PubChem