Heterocyclic Building Blocks-Oxazolidine

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2,6-Dichloropurine(SMILESS: C2=NC1=C(C(=NC(=N1)Cl)Cl)[NH]2,cas:5451-40-1) is researched.Category: oxazolidine. The article 《Multifunctional lipophilic purines: a coping strategy for anti-counterfeiting, lipid droplet imaging and latent fingerprint development》 in relation to this compound, is published in Materials Chemistry Frontiers. Let’s take a look at the latest research on this compound (cas:5451-40-1).

Nowadays, multifunctional materials based on fluorescent small mols. have bright prospects for the development of materials science. However, those materials, based on purine derivatives in particular, still face challenges and need to be further explored. In this study, a new multifunctional small mol. (CDP) based on the purine skeleton was readily synthesized, and its lipophilicity and fluorescence properties were improved by introducing dodecyl groups and carbazole groups. CDP could not only be assembled as anti-counterfeiting inks with waterproofing, ideal light stability and good fluorescence contrast, but also be applied in lipid droplet imaging of living cells. More importantly, CDP provided a simple, efficient, and widely applicable visualization method of latent fingerprints and achieved information extraction down to a minutiae level of latent fingerprints on multiple substrates. Overall, the present work supplied a new strategy for the development of multifunctional fluorescent mol. materials in mol. design and practical applications.

I hope my short article helps more people learn about this compound(2,6-Dichloropurine)Recommanded Product: 2,6-Dichloropurine. Apart from the compound(5451-40-1), you can read my other articles to know other related compounds.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Category: oxazolidine. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: Oxazole, is researched, Molecular C3H3NO, CAS is 288-42-6, about Nickel-catalyzed cross-electrophile coupling of aryl bromides and cyclic secondary alkyl bromides with spiro-bidentate-pyox ligands. Author is Gao, Nanxing; Li, Yanshun; Cao, Guorui; Teng, Dawei.

The cross-electrophile coupling of aryl bromides RBr [R = Ph, 4-(ethoxycarbonyl)phenyl, 1-(1H-indol-1-yl)ethan-1-one, etc.] and cyclic secondary alkyl bromides I [R1 = ethoxycarbonyl, (benzyloxy)carbonyl, (4-methylbenzene)sulfonyl, etc., X = (CH2)n, n = 1, 2] catalyzed by nickel/spiro-bidentate-pyox ligands, e.g., II, with lithium chloride as the additive for the Csp2-Csp3 bond formation is reported. The reaction could tolerate functional groups such as sulfonamide, ester, aldehyde, ketone, protected indolyl, tert-butoxycarbonyl, aryl nitriles and aryl chloride. Various aryl-cyclic secondary alkyl Csp2-Csp3 bond products, e.g., III, were synthesized under optimal reaction conditions (19 examples).

Here is just a brief introduction to this compound(288-42-6)Category: oxazolidine, more information about the compound(Oxazole) is in the article, you can click the link below.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

COA of Formula: C5H7BrO3. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Ethyl 3-bromo-2-oxopropanoate, is researched, Molecular C5H7BrO3, CAS is 70-23-5, about A selective “”turn-on”” sensor for recognizing In3+ and Zn2+ in respective systems based on imidazo[2,1-b]thiazole. Author is Xu, Yuankang; Zhao, Songfang; Zhang, Yanxia; Wang, Hanyu; Yang, Xiaofeng; Pei, Meishan; Zhang, Guangyou.

A new simple and easily synthesized multitarget sensor, (E)-N′-(4-(diethylamino)-2-hydroxybenzylidene)imidazo[2,1-b]thiazole-6-carbohydrazide (X), was designed and synthesized using imidazo[2,1-b]thiazole-6-carboxylic acid and 4-(diethylamino)-2-hydroxybenzaldehyde. X could be used as a sensor to detect In3+ in DMF-H2O buffer solution and detect Zn2+ in EtOH-H2O buffer solution through fluorescence enhancement with detection limits of 1.02 × 10-9 M and 5.5 × 10-9 M, resp. X exhibited an efficient “”off-on-off”” fluorescence behavior by cyclic addition of metal ions (In3+ and Zn2+) and EDTA. The stoichiometry between X and metal ions (In3+ and Zn2+) was 1 : 1. The binding mode and sensing mechanism of X with metal ions (In3+ and Zn2+) was verified by theor. calculations using Gaussian 09 based on B3LYP/6-31G(d) and B3LYP/LANL2DZ basis, resp. Moreover, X could be applied as a potential sensor for the quant. detection of In3+ and Zn2+ with a satisfactory recovery and relative standard deviation (RSD) in real water samples.

Here is just a brief introduction to this compound(70-23-5)COA of Formula: C5H7BrO3, more information about the compound(Ethyl 3-bromo-2-oxopropanoate) is in the article, you can click the link below.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

An, Seungchan; Kim, Gyudong; Kim, Hyun Jin; Ahn, Sungjin; Kim, Hyun Young; Ko, Hyejin; Hyun, Young Eum; Nguyen, Mai; Jeong, Juri; Liu, Zijing; Han, Jinhe; Choi, Hongseok; Yu, Jinha; Kim, Ji Won; Lee, Hyuk Woo; Jacobson, Kenneth A.; Cho, Won Jea; Kim, Young-Mi; Kang, Keon Wook; Noh, Minsoo; Jeong, Lak Shin published an article about the compound: 2,6-Dichloropurine( cas:5451-40-1,SMILESS:C2=NC1=C(C(=NC(=N1)Cl)Cl)[NH]2 ).Formula: C5H2Cl2N4. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:5451-40-1) through the article.

Following our report that A3 adenosine receptor (AR) antagonist 1 exhibited a polypharmacol. profile as a dual modulator of peroxisome proliferator-activated receptor (PPAR)γ/δ, we discovered a new template, 1′-homologated adenosine analogs 4a-4t, as dual PPARγ/δ modulators without AR binding. Removal of binding affinity to A3AR was achieved by 1′-homologation, and PPARγ/δ dual modulation was derived from the structural similarity between the target nucleosides and PPAR modulator drug, rosiglitazone. All the final nucleosides were devoid of AR-binding affinity and exhibited high binding affinities to PPARγ/δ but lacked PPARα binding. 2-Cl derivatives exhibited dual receptor-binding affinity to PPARγ/δ, which was absent for the corresponding 2-H derivatives 2-Propynyl substitution prevented PPARδ-binding affinity but preserved PPARγ affinity, indicating that the C2 position defines a pharmacophore for selective PPARγ ligand designs. PPARγ/δ dual modulators functioning as both PPARγ partial agonists and PPARδ antagonists promoted adiponectin production, suggesting their therapeutic potential against hypoadiponectinemia-associated cancer and metabolic diseases.

Here is just a brief introduction to this compound(5451-40-1)Formula: C5H2Cl2N4, more information about the compound(2,6-Dichloropurine) is in the article, you can click the link below.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Porter, A. E. A.; Sammes, Peter G. published an article about the compound: 6-Hydroxy-2-methylpyrimidin-4(3H)-one( cas:1194-22-5,SMILESS:CC1=NC(=CC(N1)=O)O ).Computed Properties of C5H6N2O2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1194-22-5) through the article.

The adducts I and II are prepared from III and IV and the dienophiles, MeO2CCCCO2Me and norbornadiene, resp. Brevianamide A, previously isolated from Penicillium brevi-compactum [Birch, J. A. and Wright, J. J. (1969)], may be obtained in nature by a similar process.

Here is just a brief introduction to this compound(1194-22-5)Computed Properties of C5H6N2O2, more information about the compound(6-Hydroxy-2-methylpyrimidin-4(3H)-one) is in the article, you can click the link below.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Xu, Yuankang; Wang, Hanyu; Zhao, Jinyan; Yang, Xiaofeng; Pei, Meishan; Zhang, Guangyou; Zhang, Yanxia published the article 《A dual functional fluorescent sensor for the detection of Al3+ and Zn2+ in different solvents》. Keywords: dual functional fluorescent sensor aluminum zinc detection solvent.They researched the compound: Ethyl 3-bromo-2-oxopropanoate( cas:70-23-5 ).Application of 70-23-5. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:70-23-5) here.

(E)-N’-((2-Hydroxynaphthalen-1-yl)methylene)imidazo[2,1-b]thiazole-6-carbohydrazide (X), a new fluorescent sensor, was designed and synthesized based on imidazo[2,1-b]thiazole and 2-hydroxy-1-naphthaldehyde, which could be used to detect Al3+ in methanol buffer solution and detect Zn2+ in ethanol buffer solution with detection limits of 1.45 × 10-7 M and 1.29 × 10-8 M, resp. X showed high sensitivity and selectivity towards Al3+ and Zn2+ in the presence of other metal ions. The fluorescence intensity of X was reversible even after six cycles with the sequentially alternative addition of metal ions (Al3+ and Zn2+) and PPi, showing an efficient off-on-off fluorescence behavior. The complexation ratio of X to Al3+ and Zn2+ was 1 : 1, which was proved by mass spectrometry and the B-H equation. The binding mode and sensing mechanism of X with metal ions (Al3+ and Zn2+) were verified by DFT/TDDFT calculations using Gaussian 09 based on the B3LYP/6-31G(d) basis set.

Compound(70-23-5)Application of 70-23-5 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Ethyl 3-bromo-2-oxopropanoate), if you are interested, you can check out my other related articles.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

COA of Formula: Br2Cu. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Cupric bromide, is researched, Molecular Br2Cu, CAS is 7789-45-9, about Layered Copper-Metallated Covalent Organic Frameworks for Huisgen Reactions. Author is Romero-Muniz, Ignacio; Albacete, Pablo; Platero-Prats, Ana E.; Zamora, Felix.

Covalent organic frameworks (COFs) are porous materials formed through condensation reactions of organic mols. via the formation of dynamic covalent bonds. Among COFs, those based on imine and β-ketoenamine linkages offer an excellent platform for binding metallic species such as copper to design efficient heterogeneous catalysts. In this work, imine- and β-ketoenamine-based COF materials were modified with catalytic copper sites following a metalation method, which favored the formation of binding amine defects. The obtained copper-metalated COF materials were tested as heterogeneous catalysts for 1,3-dipolar cycloaddition reactions, resulting in high yields and recyclability.

Compound(7789-45-9)COA of Formula: Br2Cu received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Cupric bromide), if you are interested, you can check out my other related articles.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

Quality Control of Cupric bromide. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Cupric bromide, is researched, Molecular Br2Cu, CAS is 7789-45-9, about Colored Janus nanocylinders driven by supramolecular coassembly of donor and acceptor building blocks. Author is Choisnet, Thomas; Canevet, David; Salle, Marc; Lorthioir, Cedric; Bouteiller, Laurent; Woisel, Patrice; Niepceron, Frederick; Nicol, Erwan; Colombani, Olivier.

Janus nanocylinders exhibit nanometric dimensions, a high aspect ratio, and two faces with different chemistries (Janus character), making them potentially relevant for applications in optics, magnetism, catalysis, surface nanopatterning, or interface stabilization, but they are also very difficult to prepare by conventional strategies. In the present work, Janus nanocylinders were prepared by supramol. coassembly in water of two different polymers functionalized with complementary assembling units. The originality of our approach consists in combining charge transfer complexation between electron-rich and electron-poor units with hydrogen bonding to (1) drive the supramol. formation of one-dimensional structures (cylinders), (2) force the two polymer arms on opposite sides of the cylinders independently of their compatibility, resulting in Janus nanoparticles, and (3) detect coassembly through a color change of the solution upon mixing of the functional polymers.

Compound(7789-45-9)Quality Control of Cupric bromide received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Cupric bromide), if you are interested, you can check out my other related articles.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Convergent synthesis of 2-thioether-substituted (N)-methanocarba-adenosines as purine receptor agonists, published in 2021, which mentions a compound: 5451-40-1, mainly applied to thioether methanocarba adenosine purine receptor agonist convergent synthesis, Recommanded Product: 2,6-Dichloropurine.

A linear route has been used to prepare (N)-methanocarba-nucleoside derivatives, which serve as purine receptor ligands having a pre-established, receptor-preferred conformation. To introduce this rigid ribose substitute, a Mitsunobu reaction of a [3.1.0]bicyclohexane 5′-trityl intermediate 3 with a nucleobase is typically followed by functional group modifications. We herein report an efficient scalable convergent synthesis for 2-substituted (N)-methanocarba-adenosines, which were demonstrated to bind to the A3 adenosine receptor. The adenine moiety was pre-functionalized with 2-thioethers and other groups before coupling to the bicyclic precursor (3) as a key step to facilitate a high yield Mitsunobu product. This new approach provided the (N)-methanocarba-adenosines in moderate to good yield, which effectively increased the overall yield compared to a linear synthesis and conserved a key intermediate 3 (a product of nine sequential steps). The generality of this convergent synthesis, which is suitable as an optimized preclin. synthetic route, was demonstrated with various 2-thioether and 2-methoxy substituents.

Compound(5451-40-1)Recommanded Product: 2,6-Dichloropurine received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(2,6-Dichloropurine), if you are interested, you can check out my other related articles.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Mixed ligand complexes of copper(II) with benzoyltrifluoroacetone, 1,10-phenanthroline and 2,2′-bipyridine: Structure, spectroscopic and antimicrobial properties, published in 2022-02-15, which mentions a compound: 7789-45-9, Name is Cupric bromide, Molecular Br2Cu, Application of 7789-45-9.

Mixed ligand copper(II) complexes of Benzoyltrifluoroacetone (BTAH) with 1,10-phenanthroline (Phen) and 2,2′-bipyridine (Bipy) were synthesized and characterized. These complexes, namely [Cu(BTA)(Phen)(NO3)] (1), [Cu(BTA)(Phen)Cl] (2), [Cu(BTA)(Bipy)(NO3)] (3), [Cu(BTA)(Bipy)Cl] (4), and [Cu(BTA)(Phen)Br]•H2O (5), were characterized by elemental anal.; spectral; magnetic and molar conductance measurements; mass spectrometry; thermal anal. and antimicrobial susceptibility testing. The structures of 1 and 4 contained square pyramidal copper(II) environments. The microbiostatic activity revealed that the copper complexes showed pronounced activity in all the tested bacteria, except in Klebsiella pneumonia, Escherichia coli and Salmonella enterica in which some of the complexes were moderately active on the bacterial strains.

Compound(7789-45-9)Application of 7789-45-9 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(Cupric bromide), if you are interested, you can check out my other related articles.

Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem