Chemistry can be defined as the study of matter and the changes it undergoes. Safety of (R)-4-Benzyl-2-oxazolidinone. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.Safety of (R)-4-Benzyl-2-oxazolidinone, Name is (R)-4-Benzyl-2-oxazolidinone, molecular formula is C10H11NO2, introducing its new discovery.
The enantiomers of 8-<<(4-chlorophenyl)sulfonyl>amino>-4-(3-pyridinylpropyl)octanoic acid (1) and its pyridinyl ether analog (2) were synthesized using the highly diastereoselective method of alkylation of acyloxazolidinone.These enantiomerically pure compounds were compared with the corresponding racemic compounds 1 and 2 for their in vitro activity.Compounds 1, 1R, and 1S and 2, 2S, and 2R were equipotent as thromboxane receptor antagonists (TxRAS) and thromboxane synthase inhibitors (TxSIs) (IC50 = 2-30 nM).Upon oral administration to guinea pigs, the enantiomers inhibited the ex vivo U 46619-induced platelet aggregation with potency similar to that of the corresponding racemic compound.This indicates that the enantiomers have pharmacologic profile and bioavailability similar to that of tha corresponding racemic compound.
Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.Read on for other articles about 102029-44-7
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H1734NO – PubChem