Srinivasarao, Talasila; Mohanty, Sandeep; Venkata, Suryanarayana C. H.; Reddy, G. Sandeep; Jaydeepkumar; Rao, B. Venkateswara published the article 《An efficient and novel process for the synthesis of nizatidine》. Keywords: dimethylamino ethanethioamide ethyl bromopyruvate green cyclocondensation reduction amination; nizatidine preparation.They researched the compound: Ethyl 3-bromo-2-oxopropanoate( cas:70-23-5 ).SDS of cas: 70-23-5. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:70-23-5) here.
A facile eco-friendly, cost effective and robust process for the synthesis of Nizatidine via the cyclocondensation of 2-(dimethylamino)ethanethioamide with Et bromopyruvate followed by reduction then coupled with cysteamine hydrochloride. The later formed product was coupled with N-methyl-1-(methylthio)-2-nitroethenamine in water resulted Nizatidine. The synthesized product met European pharmacopeia (EP) monograph.
In some applications, this compound(70-23-5)SDS of cas: 70-23-5 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H7NO – PubChem