One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: Oxazolidin-2-one, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 497-25-6, Name is Oxazolidin-2-one, molecular formula is C3H5NO2
In this study, the hepatoprotective activity of methanol bark extract of Alangium salviifolium (BEA) was evaluated for biochemical and histological parameters in swiss albino mice with CCl4-induced hepatotoxicity. The hepatomodulatory effect of two doses of BEA (20 and 50 mg/kg bw for 15 days by oral gavage) was assessed on antioxidant enzymes, phase I and phase II drug detoxifying enzymes. For the characterization of the extract, GC-MS analysis was performed that revealed the abundance of alkaloids and steroidal compounds. Total phenolic and flavonoid contents in BEA were 69.61 ± 0.18 mg GAE/g and 46.27 ± 3.44 mg Rutin/g, respectively. BEA administration decreased the levels of AST, ALT, and ALP, which were elevated due to hepatic damage by CCl4. BEA significantly decreased the lipid peroxidation, activities of LDH, and phase I enzymes including cytochrome P450 reductase, cytochrome b5 reductase while increased the activities of SOD, CAT, and phase II enzymes DT-diaphorase and glutathione S-transferase in liver. Further, histological evaluation of the liver tissue was suggestive of the protective effect of BEA against CCl4 toxicity. Together, these results suggest that BEA has strong hepatoprotective activity in mice which may also be attributed to its potential chemopreventive efficacy.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: Oxazolidin-2-one, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 497-25-6, in my other articles.
Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H489NO – PubChem