99395-88-7, (S)-4-Phenyloxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(S) -4-phenyl-2-oxazolidinone was added to a 250 mL three-necked flask, 83 g (48 mmol), DIPEA (15 mL)Anhydrous dichloromethane 144 mL,DMF 3 drops and DMAP catalytic amount, heated to reflux, and slowly dropwise 11.5 g (72 mmol) of methyl chlorocaproate.Reflux reaction for 3 hours,TLC showed that the reaction was complete with 1M dilute hydrochloric acid to terminate the reaction, saturated sodium bicarbonate, saturated brine washing, anhydrous sodium sulfate drying, concentration, sand, the final column chromatography was pure 9.3g, income: 66.15%, mp : 54 C to 56 C
99395-88-7, 99395-88-7 (S)-4-Phenyloxazolidin-2-one 730424, aoxazolidine compound, is more and more widely used in various fields.
Reference£º
Patent; Nanjing University of Technology; Wang, YuBin; Xue, xiaojian; Lu, peng; Fan, chen; Qin, Hui; (20 pag.)CN103864658; (2016); B;,
Oxazolidine – Wikipedia
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