Tag: 200-300

Method for the Preparation of Nonracemic Bis-Cyclometalated Iridium(III) Complexes was written by Helms, Melanie; Lin, Zhijie; Gong, Lei; Harms, Klaus; Meggers, Eric. And the article was included in European Journal of Inorganic Chemistry in 2013.Recommanded Product: 135948-04-8 The following contents are mentioned in the article:

A practical strategy for the generation of virtually enantiomerically pure bis-cyclometalated iridium(III) complexes is reported. Accordingly, the reactions of [Ir(μ-Cl)(ppy)2]2 (ppy = cyclometalating 2-phenylpyridine) with (S)-4-tert-butyl-2-(2′-hydroxyphenyl)-2-oxazoline [(S)-1a], [Ir(μ-Cl)(pq)2]2 (pq = cyclometalating 2-phenylquinoline) with (S)-2-(2′-hydroxyphenyl)-4-isopropyl-2-oxazoline [(S)-1b], and [Ir(μ-Cl)(pbt)2]2 (pbt = cyclometalating 2-phenylbenzothiazole) with (S)-2-(2′-hydroxyphenyl)-4-isopropyl-2-thiazoline [(S)-1d] afforded diastereomeric mixtures of salicyloxazolinato or salicylthiazolinato complexes Λ/Δ-[Ir(ppy)2{(S)-1a-H}]PF6, Λ/Δ-[Ir(pq)2{(S)-1b-H}]PF6, and Λ/Δ-[Ir(pbt)2{(S)-1d-H}]PF6, resp., which could be resolved by silica gel flash chromatog. With the individual diastereomers in hand, an acid-induced substitution of the chiral auxiliaries by achiral bidentate ligands with retention of configuration afforded several iridium complexes Λ- or Δ-[Ir(C-N)2(N N)]PF6 (C-N = cyclometalating ppy, pq, or pbt; N N = 2,2′-bipyridine, 1,10-phenanthroline, or 2,2′-biquinoline) with enantiomeric ratio (er) values of 24:1 to 230:1. This study involved multiple reactions and reactants, such as (S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8Recommanded Product: 135948-04-8).

(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8) belongs to oxazolidine derivatives.Oxazolidines are readily available also from propargyl amines. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Recommanded Product: 135948-04-8

135948-04-8;(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol;The future of 135948-04-8;New trend of C13H17NO2;function of 135948-04-8

Chiral-at-Ruthenium Catalyst with Sterically Demanding Furo[3,2-b]pyridine Ligands was written by Cui, Tianjiao; Qin, Jie; Harms, Klaus; Meggers, Eric. And the article was included in European Journal of Inorganic Chemistry in 2019.Product Details of 1045894-43-6 The following contents are mentioned in the article:

A sterically demanding derivative of a previously introduced chiral-at-metal ruthenium(II) catalyst scaffold, I (Λ-3, Δ-3; Ar = 2,4,6-Me3C6H2) is introduced. It is composed of two bidentate furo[3,2-b]pyridyl functionalized N-heterocyclic carbene ligands. Their cis-coordination generates helical chirality and a stereogenic ruthenium center. Two addnl. labile acetonitriles compose the catalytic site which is highly shielded by two 2-(tert-butyl)furo[3,2-b]pyridine moieties. The synthesis of the non-racemic ruthenium catalyst and its catalytic properties for the enantioselective alkynylation of 2,2,2-trifluoroacetophenone and pentafluorobenzaldehyde are reported and compared with sterically less demanding derivatives This study involved multiple reactions and reactants, such as (R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6Product Details of 1045894-43-6).

(R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Product Details of 1045894-43-6

1045894-43-6;(R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol;The future of 1045894-43-6;New trend of C12H15NO2;function of 1045894-43-6

Synthesis of Air- and Moisture-Stable, Storable Chiral Oxorhenium Complexes and Their Application as Catalysts for the Enantioselective Imine Reduction was written by Das, Braja Gopal; Nallagonda, Rajender; Dey, Dhananjay; Ghorai, Prasanta. And the article was included in Chemistry – A European Journal in 2015.Computed Properties of C13H17NO2 The following contents are mentioned in the article:

Air-/moisture-stable, crystalline, and storable chiral salicyloxazoline based oxorhenium(V) complexes were synthesized and their catalytic application for the asym. reduction of ketimines using hydrosilane as hydride source was disclosed. A broad substrate scope, high yields, and excellent enantioselectivities (up to 99 %) were attained. Furthermore, the syntheses of enantiopure α-amino esters, γ- and δ-lactams, and isoindolinones were also carried out using this methodol. Finally, the method was applied to synthetic targets of pharmaceutical relevance, such as R-(+)-salsolidine and R-(+)-crispine A. This study involved multiple reactions and reactants, such as (S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8Computed Properties of C13H17NO2).

(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8) belongs to oxazolidine derivatives. Oxazolidines that are the precursor to bisoxazolidines are in effect mono-oxazolidines. They are also used as moisture scavengers in polyurethane and other systems. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries.Computed Properties of C13H17NO2

135948-04-8;(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol;The future of 135948-04-8;New trend of C13H17NO2;function of 135948-04-8

Synthesis of Air- and Moisture-Stable, Storable Chiral Oxorhenium Complexes and Their Application as Catalysts for the Enantioselective Imine Reduction was written by Das, Braja Gopal; Nallagonda, Rajender; Dey, Dhananjay; Ghorai, Prasanta. And the article was included in Chemistry – A European Journal in 2015.SDS of cas: 163165-92-2 The following contents are mentioned in the article:

Air-/moisture-stable, crystalline, and storable chiral salicyloxazoline based oxorhenium(V) complexes were synthesized and their catalytic application for the asym. reduction of ketimines using hydrosilane as hydride source was disclosed. A broad substrate scope, high yields, and excellent enantioselectivities (up to 99 %) were attained. Furthermore, the syntheses of enantiopure α-amino esters, γ- and δ-lactams, and isoindolinones were also carried out using this methodol. Finally, the method was applied to synthetic targets of pharmaceutical relevance, such as R-(+)-salsolidine and R-(+)-crispine A. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2SDS of cas: 163165-92-2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.SDS of cas: 163165-92-2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

Probing Chiral Recognition of Enzyme Active Sites with Octahedral Iridium(III) Propeller Complexes was written by Goebel, Peter; Ritterbusch, Florian; Helms, Melanie; Bischof, Matthias; Harms, Klaus; Jung, Manfred; Meggers, Eric. And the article was included in European Journal of Inorganic Chemistry in 2015.Computed Properties of C13H17NO2 The following contents are mentioned in the article:

Chiral bis-cyclometalated octahedral organoiridium(III) complexes were designed to target different classes of enzymes, namely carbonic anhydrases, histone deacetylases, and serine proteases. The stereoselective non-racemic synthesis of selected complexes was used to study the chiral discrimination of enzyme active sites for enantiomers of propeller-type octahedral metal complexes. Cases for negligible, modest, and significant chiral discrimination in the interaction of iridium propeller complexes with enzyme active sites were identified. This study involved multiple reactions and reactants, such as (S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8Computed Properties of C13H17NO2).

(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Computed Properties of C13H17NO2

135948-04-8;(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol;The future of 135948-04-8;New trend of C13H17NO2;function of 135948-04-8

Further Studies on the [1,2]-Wittig Rearrangement of 2-(2-Benzyloxy)aryloxazolines was written by Aitken, R. Alan; Harper, Andrew D.; Inwood, Ryan A.. And the article was included in Molecules in 2022.Formula: C15H13NO2 The following contents are mentioned in the article:

The behavior of 14 ortho-functionalized 2-aryloxazolines (11 of them prepared and characterized for the first time) with butyllithium had been examined Significant limitations to the Wittig rearrangement of such systems were revealed. In terms of asym. Wittig rearrangement, good diastereoselectivity was obtained with a valine-derived 4-iso-Pr oxazoline, but this was compromised by racemization upon hydrolysis. More encouraging selectivity was achieved in the Wittig rearrangement of an acyclic phenylalanine-derived ortho-benzyloxy benzamide. This study involved multiple reactions and reactants, such as (R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4Formula: C15H13NO2).

(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries.Formula: C15H13NO2

150699-08-4;(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol;The future of 150699-08-4;New trend of C15H13NO2;function of 150699-08-4

Further Studies on the [1,2]-Wittig Rearrangement of 2-(2-Benzyloxy)aryloxazolines was written by Aitken, R. Alan; Harper, Andrew D.; Inwood, Ryan A.. And the article was included in Molecules in 2022.Computed Properties of C16H15NO2 The following contents are mentioned in the article:

The behavior of 14 ortho-functionalized 2-aryloxazolines (11 of them prepared and characterized for the first time) with butyllithium had been examined Significant limitations to the Wittig rearrangement of such systems were revealed. In terms of asym. Wittig rearrangement, good diastereoselectivity was obtained with a valine-derived 4-iso-Pr oxazoline, but this was compromised by racemization upon hydrolysis. More encouraging selectivity was achieved in the Wittig rearrangement of an acyclic phenylalanine-derived ortho-benzyloxy benzamide. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Computed Properties of C16H15NO2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries.Computed Properties of C16H15NO2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

Adding the right (or left) twist to tris-chelate complexes – coordination chemistry of chiral oxazolylphenolates with M3+ ions (M = Al or lanthanide) was written by Aspinall, Helen C.; Bacsa, John; Beckingham, Oliver D.; Eden, Edward G. B.; Greeves, Nicholas; Hobbs, Matthew D.; Potjewyd, Frances; Schmidtmann, Marc; Thomas, Christopher D.. And the article was included in Dalton Transactions in 2014.Computed Properties of C16H15NO2 The following contents are mentioned in the article:

Homoleptic tris-chelate complexes ML3 (M = Al or rare earth; L = chiral or achiral oxazolyl-phenolate or -naphtholate) is reported. In all cases, complexes crystallize as mer-isomers and complete diastereoselectivity is observed on crystallization of the complexes: ML3 crystallize with Λ-helicity at the metal where L = (S)-oxazolylphenolate. Complexes were characterized in solution by NMR spectroscopy, demonstrating rapid ligand exchange at ambient temperature for rare earth complexes, and slow exchange on the NMR timescale for complexes of Al; in all cases the mer-isomer is observed exclusively. Crystal structures are reported for [YL3]2 (L = (S)-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-phenolate), mer-[YbL3] (L = (S)-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-6-methylphenolate) and mer-[AlL3] (L = (S)-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-6-methylphenolate, (S)-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-6-cyanophenolate, (S)-1-(4-isopropyl-4,5-dihydrooxazol-2-yl)naphthalen-2-olate, 1-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)naphthalen-2-olate). This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Computed Properties of C16H15NO2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds are well-known chiral auxiliaries and strategic molecular moieties in chemistry since they can effectively mask or mimic amino acid units or amino alcohols. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Computed Properties of C16H15NO2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

Enantioselective Allylation of Aldehydes with (Dialkoxyallyl)chromium(III) Complexes was written by Sugimoto, Kazuyuki; Aoyagi, Sakae; Kibayashi, Chihiro. And the article was included in Journal of Organic Chemistry on April 18,1997.HPLC of Formula: 163165-92-2 The following contents are mentioned in the article:

A (dialkoxyallyl)chromium(III) complex, chirally modified by an N-benzoyl-L-prolinol derivative, led to high induction in the asym. preparation of homoallylic alcs. by allyl coupling with aldehydes. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2HPLC of Formula: 163165-92-2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.HPLC of Formula: 163165-92-2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

Cobalt/Salox-Catalyzed Enantioselective C-H Functionalization of Arylphosphinamides was written by Yao, Qi-Jun; Chen, Jia-Hao; Song, Hong; Huang, Fan-Rui; Shi, Bing-Feng. And the article was included in Angewandte Chemie, International Edition on June 20,2022.Reference of 163165-92-2 The following contents are mentioned in the article:

Previous methods on Co(III)-catalyzed asym. C-H activation rely on the use of tailor-made cyclopentadienyl-ligated Co(III) complexes, which require lengthy steps for the preparation Herein, the authors report an unprecedented enantioselective C-H functionalization enabled by a simple Co/salicyloxazoline (Salox) catalysis. The chiral Salox ligands can be easily prepared in one step from salicylonitrile and chiral amino alcs. A broad range of P-stereogenic compounds were synthesized in high yields with excellent enantioselectivities (45 examples, up to 99% yield and >99% ee). The isolation and characterization of several intermediates provided insights into the generation of active catalytic Co species, the action of Salox, and the mode of stereocontrol. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Reference of 163165-92-2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.Reference of 163165-92-2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2