Tag: 200-300

Remarkable reversal of the non-linear effect in the catalytic enantioselective allylic oxidation of cyclohexene using copper proline complexes and t-butyl hydroperoxide was written by Zondervan, Charon; Feringa, Ben L.. And the article was included in Tetrahedron: Asymmetry on July 12,1996.Product Details of 163165-92-2 The following contents are mentioned in the article:

Several examples of efficient catalytic conversions of cyclohexene to optically active 2-cyclohexenyl propionate are reported using t-Bu hydroperoxide as oxidant. With the bis-(S)-prolinato copper(II) complex enantioselectivities up to 63% with good conversions were obtained. A neg. non-linear ligand effect was observed Addition of catalytic amounts of anthraquinone resulted in a higher enantioselectivity as well as a reversal of the non-linear effect. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Product Details of 163165-92-2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. In another report, the incorporation of an additional substituted oxazolidine ring over a range of new biphenylazepinium salt organocatalysts for the asymmetric epoxidation of alkenes improved enantiocontrol over the parent structures.Product Details of 163165-92-2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

Chiral-Auxiliary-Mediated Asymmetric Synthesis of Tris-Heteroleptic Ruthenium Polypyridyl Complexes was written by Gong, Lei; Mulcahy, Seann P.; Harms, Klaus; Meggers, Eric. And the article was included in Journal of the American Chemical Society on July 22,2009.Related Products of 1045894-43-6 The following contents are mentioned in the article:

A strategy for the asym. synthesis of chiral-at-metal [Ru(pp)(pp’)(pp”)]+ complexes (Hpp = isopropyl-2-(2′-hydroxyphenyl)oxazoline, pp’ and pp” = achiral 2,2′-bipyridine, 5,5′-dimethyl- and 4,4′-di-tert-butyl-2,2′-bipyridine), is reported. The method employs isopropyl-2-(2′-hydroxyphenyl)oxazolines as chiral auxiliaries, which serve in their deprotonated forms as strong bidentate ligands that provide excellent asym. induction in the coordination chem. and, importantly, can afterward become substituted with complete retention of configuration in the presence of acid. This study involved multiple reactions and reactants, such as (R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6Related Products of 1045894-43-6).

(R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol (cas: 1045894-43-6) belongs to oxazolidine derivatives. Oxazolidines that are the precursor to bisoxazolidines are in effect mono-oxazolidines. They are also used as moisture scavengers in polyurethane and other systems. Oxazolidines are commonly used as metal ligands in asymmetric catalysis, synthetic intermediates in organic synthesis, and also used as the protecting groups.Related Products of 1045894-43-6

1045894-43-6;(R)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)phenol;The future of 1045894-43-6;New trend of C12H15NO2;function of 1045894-43-6

Chiral Pd-, Cu- and Ni-chelates and their utilities as catalysts in allylic acetoxylation of alkenes was written by Yang, Hu; Khan, Masood A.; Nicholas, Kenneth M.. And the article was included in Journal of Molecular Catalysis on July 29,1994.Quality Control of (R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol The following contents are mentioned in the article:

A series of chiral ML*2 complexes of Pd, Cu and Ni [L = 2-trifluoroacetylcamphorato (tfacam), (R)-N-α-methylbenzylsalicylaldimine, 2-(2′-phenolato)-4-substituted oxazoline (phenox)] were prepared and characterized, including x-ray structures of Pd(tfacam)2 (1) and Pd(4-Ph-phenox)2 (3a). The Pd- and Cu-chelates are active (pre)catalysts for the allylic acetoxylation of alkenes. The yields and chemoselectivities in these reactions are high but little enantioselectivity (0-5%) was found. Several mechanistic probes, including tests of the stability of the product and PdL*2 under the reaction conditions, the product distribution from the acetoxylation of D-1-cyclohexene, and the low acetolysis reactivity of LPd(η3-allyl), indicate the intervention of (η3-allyl)-Pd intermediates in the catalytic process in which either or both L groups dissociate or at least dechelate in the product-forming step. This study involved multiple reactions and reactants, such as (R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4Quality Control of (R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol).

(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4) belongs to oxazolidine derivatives.Oxazolidines are readily available also from propargyl amines. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol. Oxazolidines are weaker bases (pKa 6–7) than parent β-amino alcohols and found to be more lipophilic than the parent compound at physiological pH.Quality Control of (R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol

150699-08-4;(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol;The future of 150699-08-4;New trend of C15H13NO2;function of 150699-08-4

Enantioselective addition of diethylzinc to aromatic aldehydes with chiral 2-oxazolinyl phenol as catalysts was written by Li, Xin-sheng; Wu, Xiao-hua; Fang, Ke-ming. And the article was included in Zhejiang Shifan Daxue Xuebao, Ziran Kexueban on November 30,2005.Electric Literature of C16H15NO2 The following contents are mentioned in the article:

Chiral 2-oxazolinyl phenols were prepared and applied in the addition reaction of diethylzinc to aromatic aldehydes with moderate enantioselectivity. Ligand I was found to show the best asym. induction in the addition reaction of p-chlorobenzaldehyde to provide sec-alc. with 85% yield and 63% ee. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Electric Literature of C16H15NO2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives.Oxazolidines are readily available also from propargyl amines. In another report, the incorporation of an additional substituted oxazolidine ring over a range of new biphenylazepinium salt organocatalysts for the asymmetric epoxidation of alkenes improved enantiocontrol over the parent structures.Electric Literature of C16H15NO2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

Enantioselective addition of diethylzinc to aromatic aldehydes with chiral 2-oxazolinyl phenol as catalysts was written by Li, Xin-sheng; Wu, Xiao-hua; Fang, Ke-ming. And the article was included in Zhejiang Shifan Daxue Xuebao, Ziran Kexueban on November 30,2005.Product Details of 150699-08-4 The following contents are mentioned in the article:

Chiral 2-oxazolinyl phenols were prepared and applied in the addition reaction of diethylzinc to aromatic aldehydes with moderate enantioselectivity. Ligand I was found to show the best asym. induction in the addition reaction of p-chlorobenzaldehyde to provide sec-alc. with 85% yield and 63% ee. This study involved multiple reactions and reactants, such as (R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4Product Details of 150699-08-4).

(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4) belongs to oxazolidine derivatives. A common way to produce multisubstituted oxazolidines is by means of cycloaddition reactions. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Product Details of 150699-08-4

150699-08-4;(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol;The future of 150699-08-4;New trend of C15H13NO2;function of 150699-08-4

The Synthesis of Novel Oxazolinylphosphinic Esters and Amides and Application to the Cyanosilylation of Aldehydes was written by Luo, Mei. And the article was included in Current Organic Synthesis on October 31,2015.Application of 150699-08-4 The following contents are mentioned in the article:

A new class of modular functionalized oxazolines were synthesized using a simple, novel 1-pot method under inert moisture-free conditions. Then the oxazolines can be further elaborated to phosphine-containing oxazolines. The 1st step is to synthesize intermediates via the reaction of 2-hydroxybenzonitrile or 2-aminobenzonitrile with chiral amino alcs., subsequent reactions with phosphine chlorides, providing products in moderate yields. Product structures are fully characterized by NMR, IR, MS and x-ray analyses. These compounds are highly active catalysts for the cyanosilylation of prochiral benzaldehyde (20-96% yield). This study involved multiple reactions and reactants, such as (R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4Application of 150699-08-4).

(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. Oxazolidines are commonly used as metal ligands in asymmetric catalysis, synthetic intermediates in organic synthesis, and also used as the protecting groups.Application of 150699-08-4

150699-08-4;(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol;The future of 150699-08-4;New trend of C15H13NO2;function of 150699-08-4

The Synthesis of Novel Oxazolinylphosphinic Esters and Amides and Application to the Cyanosilylation of Aldehydes was written by Luo, Mei. And the article was included in Current Organic Synthesis on October 31,2015.Formula: C16H15NO2 The following contents are mentioned in the article:

A new class of modular functionalized oxazolines were synthesized using a simple, novel 1-pot method under inert moisture-free conditions. Then the oxazolines can be further elaborated to phosphine-containing oxazolines. The 1st step is to synthesize intermediates via the reaction of 2-hydroxybenzonitrile or 2-aminobenzonitrile with chiral amino alcs., subsequent reactions with phosphine chlorides, providing products in moderate yields. Product structures are fully characterized by NMR, IR, MS and x-ray analyses. These compounds are highly active catalysts for the cyanosilylation of prochiral benzaldehyde (20-96% yield). This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Formula: C16H15NO2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. A common way to produce multisubstituted oxazolidines is by means of cycloaddition reactions. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries.Formula: C16H15NO2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

(η3-Allyl)palladium complexes of chiral N,O-chelates: preparation, structures, and prospects for selective allylic functionalization was written by Yang, Hu; Khan, Masood A.; Nicholas, Kenneth M.. And the article was included in Organometallics on September 30,1993.Name: (R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol The following contents are mentioned in the article:

A series of (η3-allyl)Pd derivatives of chiral N,O-bidentate ligands have been prepared and characterized to assess their potential as model intermediates for regio- and stereocontrolled catalytic allylic oxidation and substitution reactions. [N-(α-methylbenzyl)salicylaldimine]-Pd(η3-cyclohexenyl) (I), which exists in solution as a 1:1 Pd-allyl rotameric (exo/endo) mixture, selectively crystallizes as a single isomer. The X-ray crystal structure of this isomer of I shows nearly sym. Pd-allyl bonding parameters and the N-α-Ph group endo to the flap of the cyclohexenyl ring. The new chiral 4-substituted salicyloxazoline ligands and the corresponding (salicyloxazoline)Pd(η3-cyclohexenyl) complexes (II, R = Ph, CMe3, etc.; R1 = H, NO2, OMe; R2 = H, NO2) have been prepared in good yields by treatment of {(η3-cyclohexenyl)PdCl}2 with the K derivatives of the ligands. Solution NMR studies of II indicate that the ratio of isomers is a function of the size of the α-N substituent, with single isomers being present for R = tert-Bu. X-ray anal. of II (R = CMe3, R1 = R2 = H) reveals that the tert-Bu group and the cyclohexenyl flap are in an exo relationship with little evidence for a differential ground-state trans influence derived from the unsym. chelate. The terminal allylic proton NMR resonances of II (R = CMe3) are separated by ca. 0.4-0.5 ppm, suggesting different electronic characters for the two allylic carbons. Reactivity studies show that the complexes II are relatively unreactive toward HOAc, giving varying amounts of allylic acetate, and toward the nucleophiles OAc- and CH(CO2CH3)2-. This study involved multiple reactions and reactants, such as (R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-10-8Name: (R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol).

(R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-10-8) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. As well as other multifunctional heterocyclic compounds, oxazolidine rings play an essential role in organic and medicinal chemistry, behaving, in some cases as powerful antitumor agents.Name: (R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol

150699-10-8;(R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol;The future of 150699-10-8;New trend of C13H17NO2;function of 150699-10-8

(η3-Allyl)palladium complexes of chiral N,O-chelates: preparation, structures, and prospects for selective allylic functionalization was written by Yang, Hu; Khan, Masood A.; Nicholas, Kenneth M.. And the article was included in Organometallics on September 30,1993.HPLC of Formula: 150699-08-4 The following contents are mentioned in the article:

A series of (η3-allyl)Pd derivatives of chiral N,O-bidentate ligands have been prepared and characterized to assess their potential as model intermediates for regio- and stereocontrolled catalytic allylic oxidation and substitution reactions. [N-(α-methylbenzyl)salicylaldimine]-Pd(η3-cyclohexenyl) (I), which exists in solution as a 1:1 Pd-allyl rotameric (exo/endo) mixture, selectively crystallizes as a single isomer. The X-ray crystal structure of this isomer of I shows nearly sym. Pd-allyl bonding parameters and the N-α-Ph group endo to the flap of the cyclohexenyl ring. The new chiral 4-substituted salicyloxazoline ligands and the corresponding (salicyloxazoline)Pd(η3-cyclohexenyl) complexes (II, R = Ph, CMe3, etc.; R1 = H, NO2, OMe; R2 = H, NO2) have been prepared in good yields by treatment of {(η3-cyclohexenyl)PdCl}2 with the K derivatives of the ligands. Solution NMR studies of II indicate that the ratio of isomers is a function of the size of the α-N substituent, with single isomers being present for R = tert-Bu. X-ray anal. of II (R = CMe3, R1 = R2 = H) reveals that the tert-Bu group and the cyclohexenyl flap are in an exo relationship with little evidence for a differential ground-state trans influence derived from the unsym. chelate. The terminal allylic proton NMR resonances of II (R = CMe3) are separated by ca. 0.4-0.5 ppm, suggesting different electronic characters for the two allylic carbons. Reactivity studies show that the complexes II are relatively unreactive toward HOAc, giving varying amounts of allylic acetate, and toward the nucleophiles OAc- and CH(CO2CH3)2-. This study involved multiple reactions and reactants, such as (R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4HPLC of Formula: 150699-08-4).

(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol (cas: 150699-08-4) belongs to oxazolidine derivatives. Oxazolidines are well known as key portions of bioactive molecules or precursors of chiral molecules, as well as established chiral auxiliaries. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.HPLC of Formula: 150699-08-4

150699-08-4;(R)-2-(4-Phenyl-4,5-dihydrooxazol-2-yl)phenol;The future of 150699-08-4;New trend of C15H13NO2;function of 150699-08-4

Chiral Salicyloxazolines as Auxiliaries for the Asymmetric Synthesis of Ruthenium Polypyridyl Complexes was written by Gong, Lei; Mulcahy, Seann P.; Devarajan, Deepa; Harms, Klaus; Frenking, Gernot; Meggers, Eric. And the article was included in Inorganic Chemistry on September 6,2010.SDS of cas: 135948-04-8 The following contents are mentioned in the article:

Chiral auxiliaries are promising emerging tools for the asym. synthesis of octahedral metal complexes. The authors recently introduced chiral salicyloxazolines as coordinating bidentate chiral ligands which provide excellent control over the metal-centered configuration in ligand substitution reactions and can be removed afterward in an acid-induced fashion under complete retention of configuration. Here reported is the authors’ detailed study of this sequence of reactions, affording virtually enantiopure Ru polypyridyl complexes. The control of the metal-centered chirality by the coordinated chiral salicyloxazolinate ligand was evaluated as a function of reaction conditions, the employed bidentate 2,2′-bipyridine and 1,10-phenanthroline ligands, and the substituent at the asym. 5-position of the oxazoline heterocycle. Most striking was the strong influence of the reaction solvent, with aprotic solvents of lower polarity providing the most favorable diastereoselectivities. Through a combination of computational and exptl. results, the observed stereoselectivities are under thermodn. control. The removal of the chiral salicyloxazoline auxiliary under retention of the configuration requires acidic conditions and a coordinating solvent such as MeCN or THF to prevent partial racemization. This method represents the 1st general strategy for the asym. synthesis of enantiopure heteroleptic Ru polypyridyl complexes. This study involved multiple reactions and reactants, such as (S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8SDS of cas: 135948-04-8).

(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8) belongs to oxazolidine derivatives. Oxazolidine-based compounds are well-known chiral auxiliaries and strategic molecular moieties in chemistry since they can effectively mask or mimic amino acid units or amino alcohols. In another report, the incorporation of an additional substituted oxazolidine ring over a range of new biphenylazepinium salt organocatalysts for the asymmetric epoxidation of alkenes improved enantiocontrol over the parent structures.SDS of cas: 135948-04-8

135948-04-8;(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol;The future of 135948-04-8;New trend of C13H17NO2;function of 135948-04-8