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A highly enantioselective FeII-catalyzed thia-Michael addition to alpha,beta-unsaturated carbonyl derivatives was developed. The scope of the reaction was demonstrated with a selection of aromatic, heterocyclic and aliphatic thiols, and various Michael acceptors. The corresponding beta-thioethers were obtained in good to excellent yields (up to 98%) and moderate to excellent enantioselectivities (up to 96:4 er). Unusual hepta-coordination of the metal and chelation to alpha,beta-unsaturated oxazolidin-2-one derivatives allowed the construction of a coherent model rationalizing the enantioselective event. DFT calculations support the proposed model for observed stereoselectivities.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H722NO – PubChem

 

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The addition of xanthates and vinyldisulfones across the double bond of enamides and ene-carbamates provides access to the corresponding three-component adducts in good to excellent yields with a high level of diastereocontrol in cyclic systems. This strategy illustrates a complementary reactivity for these versatile olefins and extends their scope of application.

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Oxazolidine – Wikipedia,
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alpha,beta-Unsaturated imides and alpha,beta-unsaturated esters were found to undergo alcoholysis in the presence of trimethylphosphine. The reaction is initiated by nucleophilic addition of trimethylphosphine to the double bond of the alpha,beta-unsaturated carbonyl compound. Saturated imides also undergo the alcoholysis in the presence of the corresponding alpha,beta-unsaturated imide.

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Oxazolidine – Wikipedia,
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The invention provides novel GlyT2 inhibiting compounds useful in modulating, treating, or preventing: anxiolytic disorders; a condition requiring treatment of injured mammalian nerve tissue; a condition amenable to treatment through administration of a neurotrophic factor; a neurological disorder; or obesity; an obesity-related disorder.

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. HPLC of Formula: C3H5NO2, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 497-25-6, name is Oxazolidin-2-one. In an article,Which mentioned a new discovery about 497-25-6

A series of Zr-containing Mg-Al hydrotalcite-like (HTl) precursors were prepared using co-precipitation method with Zr4+: (Al3+ + Zr4+) from 0 to 0.7. It was demonstrated by X-ray diffraction that the yield of the HTl phase declined on increasing of Zr content. Then, Mg-Al-Zr mixed oxide (CHT-Zr) catalysts were obtained by calcining of the corresponding HTl precursors and they all exhibited mesoporous structure after heat treatment. Based on systemic characterization, it was observed that the amount of Zr additive showed a great effect on the structure and acidic-basic property of CHT-Zr samples. Meanwhile, such CHT-Zr catalysts were effective catalysts for the glycerol carbonate (GLC) synthesis from glycerol and urea. Afterwards, the function of acidic and basic sites in each reaction path identified in this research was elucidated based on the reactant conversion and product selectivity. It proved that the acidic sites were inclined to promote the reaction towards GLC synthesis, while all the paths towards the by-products were significantly catalyzed by the basic sites. However, the catalysts with extra strong acidity did not facilitate the GLC production due to poisoning of surface active sites by urea adsorption. So, a well-balanced acidic-basic property was important to obtain high GLC yield with good selectivity. Among all the catalytic samples, the catalysts with Zr4+: (Al3+ + Zr4+) = 0.3 showed the best catalytic performance with 87.8% yield of GLC. Moreover, different reaction parameters such as reaction temperature, reaction time, catalyst amount and vacuum degree were investigated and optimum conditions were established. Additionally, this catalyst could be readily recycled and reused for at least four times without any activation treatment, while still possessing high activity.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H1108NO – PubChem

 

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Organic electrosynthesis has received great attention as a powerful green tool for synthesis, affording less waste production, less chemicals spent, and often fewer reaction steps than conventional methods. Functional group interconversion and C-C bond generation by imposition of a proper electrode potential is what lies behind organic electrosynthesis processes. Paired electrochemical reactions, indirect electrosynthesis, electrochemical microreactors, and the use of ionic liquids are some of the highlighted means that contribute to optimization of the overall process. Necessity to use specific organic solvents combined with supporting electrolytes is one of the main limitations to be overcome to make the electrochemical process more economically feasible when compared to nonelectrochemical processes. Numerous examples from the bench scale to industrial routes such as adiponitrile, substituted benzaldehydes, anthraquinone, fluorinated products, and succinic acid production are well described throughout this review.

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Oxazolidine – Wikipedia,
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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 497-25-6, name is Oxazolidin-2-one, introducing its new discovery. COA of Formula: C3H5NO2

The present invention concerns a process for arylating or vinylating or alkynating a nucleophilic compound. More particularly, the invention concerns arylating nitrogen-containing organic derivatives. The arylating or vinylating or alkynating process of the invention consists of reacting a nucleophilic compound with a compound carrying a leaving group and is characterized in that the reaction is carried out in the presence of an effective quantity of a catalyst based on a metallic element M selected from groups (VIII), (Ib) and (IIb) of the periodic table and at least one ligand comprising at least one imine function and at least one supplemental nitrogen atom as the chelating atoms.

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Oxazolidine – Wikipedia,
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Novel liquid disiloxanes, containing an n-propylic spacer group between the disiloxane fragment and a cyclic or non-cyclic carbamate moiety, were synthesized and characterized as liquid electrolytes. The ionic conductivity, thermal properties, viscosity and relative permittivity of these new solvents have been investigated, taking into account steric factors.

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Oxazolidine – Wikipedia,
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Multicomponent reactions (MCRs) represent an ideal organic synthesis tool for the rapid construction of complex molecules due to their step and atom economy. Compared to two-component reactions, the development of new MCRs has been greatly limited during the 170 years since the first MCR was reported. Theoretically, the trapping of an active intermediate generated from two components by a third component could change the traditional two-component reaction pathway, leading to the discovery of MCRs. We report an example of the trapping of a-imino enols generated in situ from 1-sulfonyl-1,2,3-triazoles via a-imino metal carbene species by vinylimine ions using C(2)-substituted indoles and paraformaldehyde as precursors in the presence of a rhodium(II) catalyst. The traditional enol-ketone transformation pathway was suspended by the trapping procedure and efficiently switched to an MCR pathway to produce a-amino-b-indole ketones in moderate to good yields. Unexpectedly, the resulting products and the theoretical density functional theory (DFT) calculation results indicated that the enolic carbon had a stronger nucleophilicity than the well-known traditional enamic carbon in the trapping process. The reaction mechanism was investigated using control experiments and detailed DFT calculations, and the synthetic application of the products was also illustrated. The developed strategy provides a mild and rapid access to a-amino-b-indole ketones and suggests a rationale for the discovery of MCRs by trapping an active intermediate with a third component in a traditional two-component reaction pathway.

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Oxazolidine – Wikipedia,
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The invention discloses a quercetin derivative and its preparation method and application. The preparation method first for quercetin and formaldehyde and ammonia to make quercetin Mannich base, with 2 – oxazolidine (sulfur) ketone, SOCl2 The reaction, then the quercetin phenolic hydroxyl protection, for NaNO2 Oxidation, removing the blocking group to make quercetin derivatives. The preparation of the quercetin derivative easy through the blood-brain barrier, to the brain and the central nervous system lump has an inhibitory effect. (by machine translation)

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Oxazolidine – Wikipedia,
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