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The effect of copper oxides on the thermal degradation of bismaleimide triazine (BT) prepreg has been studied with infrared spectroscopy (IR), attenuated total reflection infrared spectroscopy (ATR), and thermogravimetric analysis (TGA). The results of IR and ATR analyses indicate that the thermal degradation in the bulk BT is mainly from the epoxy constituent while that in the copper oxides contacted BT happens not only from the epoxy but also from the more stable cyanate ester constituent. From ATR, it is concluded that the BT contacted with copper oxides have a different degradation behaviour from the bulk BT and this surface related effect can extend to two microns deep into the BT prepreg from the BT/Cu interface. This is partly due to the composition difference in the BT/Cu interfaces resulting from the preferential adsorption on copper surfaces. The TGA results indicate that the BT contacted with the copper oxides degrade at a lower temperature than the bulk BT resin, and the presence of copper oxides would also change the degradation mechanisms of the BT resin.

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Oxazolidine – Wikipedia,
Oxazolidine | C3H615NO – PubChem

 

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Cyclic peptides have been attracting a lot of attention in recent decades, especially in the area of drug discovery, as more and more naturally occurring cyclic peptides with diverse biological activities have been discovered. Chemical synthesis of cyclic peptides is essential when studying their structure-activity relationships. Conventional peptide cyclization methods via direct coupling have inherent limitations, like the susceptibility to epimerization at the C-terminus, poor solubility of fully protected peptide precursors, and low yield caused by oligomerization. In this regard, chemoselective ligation-mediated cyclization methods have emerged as effective strategies for cyclic peptide synthesis. The toolbox for cyclic peptide synthesis has been expanded substantially in the past two decades, allowing more efficient synthesis of cyclic peptides with various scaffolds and modifications. This Review will explore different chemoselective ligation technologies used for cyclic peptide synthesis that generate both native and unnatural peptide linkages. The practical issues and limitations of different methods will be discussed. The advance in cyclic peptide synthesis will benefit the biological and medicinal study of cyclic peptides, an important class of macrocycles with potentials in numerous fields, notably in therapeutics.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H1231NO – PubChem

 

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Disclosed are a series of hydroxyl purine compounds and the use thereof as PDE2 or TNFalpha inhibitors, in particular, the compounds as shown in formula (I), or tautomers thereof or pharmaceutically acceptable salts thereof.

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Oxazolidine – Wikipedia,
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(E)- and (Z)-alpha-fluoroenamides could be easily prepared with high levels of chemo- and regioselectivities by hydrofluorination of readily available ynamides with HF/pyridine. The scope and limitations of this new process for the hydrofluorination of ynamides, as well as the stability of the resulting alpha-fluoroenamides, have been extensively studied. Theoretical calculations at the MP2 and B3LYP levels of theory showed that the resulting fluoroenamides exhibit geometrical and electronic properties that partially mirror those of ureas, therefore demonstrating that the hydrofluorination of ynamides provides a general, straightforward, and user-friendly approach to bioisosteres of ureas, potent building blocks for biological studies and medicinal chemistry.

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Oxazolidine – Wikipedia,
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Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful non-invasive analytical technique for chemical analyses since direct measurements at a molecular level can be performed. In this work, a survey of NMR spectroscopy applied for studies of CO2 absorption in aqueous amine solvents (amine-CO2-H2O) relevant for post-combustion CO2 capture is presented. Technical aspects of NMR experiments and the main applications with corresponding results are provided. The overview of the NMR literature in this field suggests that studies of amine-CO2-H2O systems can benefit from a further consideration of this spectroscopic technique.

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Oxazolidine – Wikipedia,
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The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt or ester thereof, wherein R1 to R8, A1 to A3 have the are as described herein and compositions including the compounds

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Oxazolidine – Wikipedia,
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The blend MEA/MDEA (5/25%wt.) was studied on the LEMEDES-CO2 lab-scale pilot plant, with representative conditions of post-combustion CO2 capture for power generation during 900 h. CO2 loadings were determined and showed average values of 0.12 and 0.40 respectively for the lean and rich solvents. Stability of the two amines, namely MEA and MDEA, was monitored using ionic chromatography; results did not show any significant degradation of MDEA during the campaign, in contrary to MEA which showed a significant degradation in the range of 0.03 points per day. Analytical methods involving GC?MS and IC were developed in order to identify potential degradation products in the liquid phase of the solvent. Study of the gaseous emissions? composition was also realized using sampling on different solid sorbents followed by thermal desorption and GC?MS analysis. A total of 22 compounds were listed including amines, organic acids, and pyrazines derivatives. 12 degradation products were found in the solvent itself and 11 in the treated flue gas among which MDEA, the constituent amine of the blend. A quantitative monitoring was carried out for formic and oxalic acids. Results showed concentrations reaching 500 mg/L for oxalic acid and 1400 mg/L for formic acid.

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Oxazolidine – Wikipedia,
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The alkylation reactions of enolates derived from the highly diastereoselective conjugate additions of lithium (R)-N-benzyl-N-alpha-methylbenzylamide (R)-1 to N,N-dimethyl crotonamide 2 and N,N-dimethyl cinnamide 3 have been investigated.The alkylations of enolates derived from 3 are shown to afford anti-alpha-alkyl-beta-amino carboxamides with excellent stereocontrol: the stereochemistry is assigned with the aid of a single crystal X-ray structure of (2R,3S,alphaR)-N,N-dimethyl-2-benzyl-3-phenyl-3-(N-benzyl-N-alpha-methylbenzylamino)propanamide (2R,3S,alphaR)-10.As a result of the difficulty encountered is hydrolysing these hindered beta-amino amides such as 10, an alternative procedure is developed involving conjugate addition-alkylations with alpha,beta-unsaturated N-acyloxazolidin-2-ones as substrates, giving selectively alkylated products which are susceptible to reductive cleavage.

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Oxazolidine – Wikipedia,
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A heat curable thermosetting epoxy resin formulation useful for making prepregs and electrical laminates containing a viscosity modifier, wherein the viscosity modifier is:(a) an optionally substituted polymer of a monovinylidene aromatic monomer, optionally having one or more further unsaturated monomers copolymerized therewith;(b) an optionally substituted polyphenylene oxide; or(c) an oxazolidone ring-containing compound.

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Oxazolidine – Wikipedia,
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Bridged flavinium organocatalysts have displayed efficacy in the diimide mediated reduction of enamides in aqueous conditions. This represents the first diimide reduction of an electron rich alkene and offers a clean alternative to the use of alkylating agents for N-alkylation.

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Reference:
Oxazolidine – Wikipedia,
Oxazolidine | C3H793NO – PubChem