99395-88-7, Name is (S)-4-Phenyloxazolidin-2-one, molecular formula is C9H9NO2, belongs to oxazolidines compound, is a common compound. In a patnet, author is Lubin, Hodney, once mentioned the new application about 99395-88-7, COA of Formula: C9H9NO2.
Synthesis of Enantiopure trans-2,5-Disubstituted Trifluoromethylpyrrolidines and (2S,5R)-5-Trifluoromethylproline
Enantiopure trans-2,5-disubstituted trifluoromethylpyrrolidines were prepared on a several gram scale starting from a readily available chiral fluorinated oxazolidine (Fox). A pure oxazolopyrrolidine intermediate could be obtained after an efficient separation by selective diastereomer destruction. The addition of various Grignard reagents on this oxazolopyrrolidine provided disubstituted pyrrolidines with moderate to complete trans diastereoselectivity. The highly valuable compound (2S,5R)-5-trifluoromethylproline could be synthesized from the same oxazolopyrrolidine intermediate via a Strecker-type reaction.
If you¡¯re interested in learning more about 99395-88-7. The above is the message from the blog manager. COA of Formula: C9H9NO2.
Reference:
Oxazolidine – Wikipedia,
,Oxazolidine | C3H7NO – PubChem